نتایج جستجو برای: uses

تعداد نتایج: 248023  

2015
Urbain Dembélé Anne Mette Lykke Yénizié Koné Bino Témé Amadou Malé Kouyaté

BACKGROUND Carapa procera is a native oil tree species with multipurpose values traditionally exploited by the local population in Southern Mali. This study focused on the assessment of local knowledge about the use of Carapa procera. METHODS Semi-structured ethnobotanical questionnaires were conducted among the ethnic groups Senufo, Fulani and Bambara in two localities in the Sudanian zone i...

2014
Adam Csakai Christina Smith Emily Davis Alexander Martinko Sara Coulup Hang Yin

A series of novel, saccharin-based antagonists have been identified for the interferon signaling pathway. Through in vitro high-throughput screening with the Colorado Center for Drug Discovery (C2D2) Pilot Library, we identified hit compound 1, which was the basis for extensive structure-activity relationship studies. Our efforts produced a lead anti-inflammatory compound, tert-butyl N-(furan-2...

Journal: :Science and technology of advanced materials 2010
Jun Kobayashi Teruo Okano

This article reviews the properties and characterization of an intelligent thermoresponsive surface, which is a key technology for cell sheet-based tissue engineering. Intelligent thermoresponsive surfaces grafted with poly(N-isopropylacrylamide) exhibit hydrophilic/hydrophobic alteration in response to temperature change. Cultured cells are harvested on thermoresponsive cell culture dishes by ...

Journal: :Bioorganic & medicinal chemistry 2007
Chan-Hee Park Jongwon Lee Hwi Young Jung Min Ji Kim Sun Ha Lim Hyung Tae Yeo Eung Chil Choi Eun Jeong Yoon Kyu Won Kim Jong Ho Cha Seok-Ho Kim Dong-Jo Chang Do-Yeon Kwon Funan Li Young-Ger Suh

The quinolone analog SQ-4004 has been identified as a potentially excellent anti-ischemic agent, which exhibited highly potent efficacy in reducing infarct volume size in vivo rat MCAO model (32.1% at 0.01mg/kg) and potent cardioprotective effect at myocardial infarction in vivo model (26.6% at 0.01mg/kg) while it exhibited highly reduced anti-bacterial activity. The mechanistic study revealed ...

2017
Zhenjian Zhuo Yuanyuan Yu Maolin Wang Jie Li Zongkang Zhang Jin Liu Xiaohao Wu Aiping Lu Ge Zhang Baoting Zhang

Aptamers are short DNA/RNA oligonucleotides capable of binding to target molecules with high affinity and specificity. The process of selecting an aptamer is called Systematic Evolution of Ligands by Exponential Enrichment (SELEX). Thanks to the inherit merits, aptamers have been used in a wide range of applications, including disease diagnosis, targeted delivery agents and therapeutic uses. To...

Journal: :Nature 1970

Journal: :The Lancet 1849

Journal: :D-Lib Magazine 2003

Journal: :Nature 1920

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