Saponins are glycosides with triterpenoid or spirostane aglycones that demonstrate various pharmacological effects against mammalian diseases. To promote the research and development of anticancer agents from saponins, this review focuses on the anticancer properties of several typical naturally derived triterpenoid saponins (ginsenosides and saikosaponins) and steroid saponins (dioscin, polyph...

Triterpenoid saponins isolated and identified from natural resources during the period April, 2007-December, 2012 are reviewed. Current techniques used in their isolation and structure determination are discussed. New triterpenoid saponins isolated along with their occurrence, selected physical data, spectroscopic methods used for their identification and the 13C NMR data of the novel aglycones...

background: holothuroids (sea cucumbers) are members of the phylum echinodermata, which produce saponins. saponins exhibit a wide spectrum of pharmacological and biological activities. in this study, we isolated the crude saponins from the body wall of the dominant iranian species of sea cucumber, holothuria leucospilota (h. leucospilota). the purpose of this study was to confirm the presence o...

Saponins are naturally occurring amphiphilic molecules and have been associated with many biological activities. The aim of the present study was to investigate whether soya saponins trigger the onset of soyabean-induced enteritis in Atlantic salmon (Salmo salar L.), and to examine if dietary soya saponins increase the epithelial permeability of the distal intestine in Atlantic salmon. Seven ex...

The n-butanol extract of the leaves Polyscias fruticosa  (L) Harms (Araliaceae) was tested for its anti-inflammatory activity plethismometrically in egg white induced paw oedema in rats, antipyretic activity and analgesic activity by writhing method phenyl butazone, paracetamol and aspirin were used as positive controls for anti-inflammatory, antipyretic and analgesic activity screening studies...

Certain saponins are bioactive compounds with anticancer, antivirus and antioxidant activities. This paper discussed inhibitory effects of saponins from Xanthoceras Sorbifolia on tyrosinase, through the research of the rate of tyrosinase catalyzed L-DOPA oxidation. The inhibition rate of tyrosinase activity presented non-linear changes with the saponins concentration. The rate reached 52.0% whe...

Etioplasts, Prolamellar Bodies, Saponins, Chromatography Prolamellar body tubules in etioplasts are composed mainly of two saponins. The determination of these saponins in leaves, etioplasts or subfractions of etioplasts is re­ commended to evaluate the concentration of these tubules in a given fraction. Using a densitometer after TLC-separation of the saponins measurements are carried out in a...

Sea cucumbers are prolific producers of a wide range of bioactive compounds. This study aimed to purify and characterize one class of compound, the saponins, from the viscera of the Australian sea cucumber Holothuria lessoni. The saponins were obtained by ethanolic extraction of the viscera and enriched by a liquid-liquid partition process and adsorption column chromatography. A high performanc...