inhibition of prostaglandin (pgs) production leads to decrease in orthodontic tooth movement (otm). it is not known whether inhibition of cyclooxygenase-1 (cox-1) or cyclooxygenase-2 (cox-2) is the key mechanism for this effect. in this study, the effect of celecoxib, a highly-selective cox-2 inhibitor, was investigated on otm in rats.four groups of male rats (seven animals in each goup) were u...

Corticotomy-assisted orthodontic treatment is an established and efficient orthodontic technique that has recently been studied in a number of publications. It has gradually gained popularity as an adjunct treatment option for the orthodontic treatment of adults. It involves selective alveolar decortication in the form of decortication lines and dots performed around the teeth that are to be mo...

prostaglandin £j (pge-^) and indomethacin, a nonstroidal antiinflammatory drug, were separately administered during ortliodontic tooth movement in rats. at the beginning, an orthodontic appliance was placed and activated in male albinos rats. in tlie first examination, the experimental group received submucosal injections of pge-y (10 mg/kg/day) near the first maxillary riglit molars, and alcoh...

This book explores current trends in orthodontics. It covers a broad range of topics over four sections: “Current Evidence on Tooth Movement,” “Digitization and Workflow,” “Orthodontics Techniques Trends,” “Early Treatment.”

objective: the gingival crevicular fluid (gcf) is an inflammatory exudate found in the gingival sulcus. the forces exerted during orthodontic treatment cause distortion of the periodontal ligament (pdl) extra-cellular matrix, resulting in some biological features that can lead to modification of both gcf volume and its components. the present study investigated the effect of orthodontic tooth m...

objectives: the purpose of this study was to evaluate whether intra-canal application of controlled direct electric current (dec) could accelerate the amount of orthodontic tooth movement (otm) in young adult mixed breed dogs. methods: fourth premolars of both jaws of five young adult mixed breed dogs were divided into two groups of control and experimental groups. orthodontic force was applied...

The purpose of this study was to investigate the effect of tooth agenesis on dentofacial structures according to the location of the absent teeth. A total of 74 subjects were classified to three main groups and four subgroups according to the location of the absent teeth. Thirteen subjects without tooth agenesis were selected as the control group. All subjects were evaluated cephalometrically. ...

INTRODUCTION The aim of this study was to investigate the variation in the amount of the orthodontically induced tooth movement in humans and potential associations between the amount of tooth movement with age and location in the mandible or maxilla. SUBJECTS AND METHODS This study included 11 participants (7 females, 4 males) with an age range of 11.3-28.6 years. In a standardized experimen...

background. this clinical trial evaluated the effect of simvastatin on space re-opening after orthodontic space closure and its effect on the gingival index (gi) and clinical attachment loss (cal). methods. 16 females, 25‒40 years old, with spaces between anterior mandibular teeth due to chronic periodontitis were participated in this study. the patients were randomly divided into control and e...

Background and Aim: Captopril is an oral angiotensin-converting-enzyme (ACE) inhibitor extensively used in the treatment of hypertension and heart failure. ACE has been suggested to function in bone cells and might therefore impact orthodontic tooth movement (OTM). Considering the controversy surrounding the effects of ACE and its inhibitors on osseous tissues, we aimed to evaluate the effect o...