There is an urgent need for new compounds for the drug development pipeline for treatment of patients with African sleeping sickness. One approach for identifying such compounds is by high throughput screening (HTS) of compound collections. For time and cost considerations, there is a need for the development of an assay that uses at least 384-well formats. To our knowledge, there are currently...

Small-scale fluctuating magnetic fields of order $n$G are observed in supernova shocks and galaxy clusters, where its amplification is likely caused by the Biermann battery mechanism. However, these cannot be amplified further without turbulent dynamo, which generates energy through stretch-twist-fold (STF) Thus, we present here novel three-dimensional magnetohydrodynamic (MHD) simulations a la...

In the draft FIPS 180-2, NIST published SHA-2 as a new version of secure hash algorithm. SHA-2 offers four secure hash algorithms including SHA-1, SHA-256, SHA-384, and SHA-512. In other words, SHA-2 may have outputs 160, 256, 384, or 512 bits of message digest. However, SHA-2 algorithm uses fixed and predefined parameters in execution. It may be vulnerable to attacks. In this paper, we propose...

In this paper we analyse the security of the SHA-3 candidate ARIRANG. We show that bitwise complementation of whole registers turns out to be very useful for constructing high-probability differential characteristics in the function. We use this approach to find nearcollisions with Hamming weight 32 for the full compression function as well as collisions for the compression function of ARIRANG ...

Purpose To evaluate morphological changes after induction of cell death in cultured monkey retinal pigment epithelial (RPE) cells by W irradiation, starvation and treatment with a peptide derived from the C.elegans ted-4 protein. Methods SYTO live cell nucleic acid stain kit, LIVE/DEAD EukoLight viability/cytotoxicity kit, T7 polymerase DNA fragmentation essay were used to visualize cellular ch...

We present a high-throughput microfluidic platform capable of quantitating up to 384 biomarkers in 4 distinct samples by immunoassay. The microfluidic device contains 384 unit cells, which can be individually programmed with pairs of capture and detection antibody. Samples are quantitated in each unit cell by four independent MITOMI detection areas, allowing four samples to be analyzed in paral...

[This corrects the article on p. 384 in vol. 57.].

BACKGROUND Prehospital spinal immobilization criteria are useful in identifying those at risk for spinal fractures, while reducing the number of patients unnecessarily immobilized. The use of immobilization criteria, without regard to mechanism of injury, has been shown to accomplish this task. AIMS The study's purpose is to examine efficacy of a prehospital spinal clearance guideline and tri...