This discussion paper is/has been under review for the journal Atmospheric Chemistry and Physics (ACP). Please refer to the corresponding final paper in ACP if available. Abstract To provide a better representation of natural ice clouds, a novel ice cloud model containing two particle habits is developed. The microphysical and optical properties of the two-habit model (THM) are compared with bo...

Th is paper proposes a new a lgor i thm which when provided the relative costs of computa­ t ion vs. probing minimizes the to ta l cost of diagnosis. Dur ing the diagnosis process the de­ cision of whether to probe or to compute is dependent on the expected costs and benefits of each al ternat ive. I t is unl ikely tha t we w i l l be able to find general analyt ic and simpleto-compute models f...

To provide a better representation of natural ice clouds, a novel ice cloud model is developed by assuming an ice cloud to consist of an ensemble of hexagonal columns and 20-element aggregates with specific habit fractions at each particle size bin. The microphysical and optical properties of this two-habit model (THM) are compared with both laboratory and in situ measurements, and its performa...

BACKGROUND Trihalomethanes (THMs) are water disinfection by-products that have been associated with bladder cancer and adverse birth outcomes. Four THMs (bromoform, chloroform, bromodichloromethane, dibromochloromethane) were measured in blood and tap water of U.S. adults in the National Health and Nutrition Examination Survey (NHANES) 1999-2006. THMs are metabolized to potentially toxic/mutage...

Trihalomethanes (THM) are undesired disinfection byproducts (DBPs) formed during water treatment. Mice exposed to DBPs showed global DNA hypomethylation and c-myc and c-jun gene-specific hypomethylation, while evidence of epigenetic effects in humans is scarce. We explored the association between lifetime THM exposure and DNA methylation through an epigenome-wide association study. We selected ...

The present study aimed to investigate the effects of miR-338 on morphine tolerance through the targeting of CXC chemokine receptor-4 (CXCR4) in a rat model of bone cancer pain (BCP). Sprague-Dawley (SD) rats were obtained and divided into model saline (n=10), model morphine (n=50), normal saline (n=10) and normal morphine (healthy rats, n=10) groups. After BCP rat model establishment, the rema...

A horizontal travelling heater method (THM) for growing cylindrical crystals from a partially filled solution zone has been investigated for the first time. By applying ampoule rotation, the whole cross section of the crystal is successively brought into contact with the liquid solution, which is effectively stirred by forced convection. This approach was used to grow single-crystalline Hgt_xCd...

Geologic disposal is a promising solution for safe permanent isolation of accumulated high-level nuclear waste from powerplants. The behavior host rock highly coupled thermally, hydromechanically, and chemically. Numerical simulations such phenomena the extremely long term (>100,000 years) large length scale (>1 km) geologic remain to be computationally challenging. In this study, methodology h...

A construct ive learning algori thm dynamical ly creates a problem-specific neural ne twork architecture rather t h a n learning o n a pre-specified architecture. W e propose a parallel vers ion of our recently presented construct ive neural ne twork learning algori thm. Parallelization provides a computat ional speedup by a fact o r of O ( t ) where t is t h e number of training ezamples. Dist...

In this paper, we first recall a previous favourable experience with the Schwarz type domain decomposition methods applied to problems of heat flow and elasticity [9, 11, 12] and then discuss a possible use of these methods for solving Darcy flow problems.