Introduction: This study aims to determine the teratogenic effects of electric mosquito repellents on mouse (Mus musculus) fetuses. The repellent used contains active ingredient dimefluthrin 0.566% (4.2 mg/matt) which was inhaled into pregnant mice during organogenesis period 6-15 days gestation. Material and Methods: A total 30 were divided five groups with six repetitions, namely C: Control g...

enamel matrix derivative emdogain (emd) is widely used in periodontal treatment in spite of the fact that its effect on the developing embryo has not been elucidated. the aim of this study was to investigate the teratogenic effect of emd on the rat embryo neural crest cells. the neural crest is a unique population of cells that migrates from the dorsal neural tube along defined pathways and pro...

Only few studies exist regarding the risk of a teratogenic effect of tramadol when used in early pregnancy. Using the Swedish Medical Birth Register, women (deliveries in 1997-2013) who had reported the use of tramadol in early pregnancy were identified. Maternal characteristics and concomitant drug use were analyzed. Among 1,682,846 women (1,797,678 infants), 1751 (1776 infants) had used trama...

BACKGROUND Ochratoxin A (OTA) is a mycotoxin produced by certain Aspergillus and Penicillium species. It has been observed to be teratogenic in a number of animal models including rat, mouse, hamster, and chick, with reduced birth weight and craniofacial abnormalities being the most commonly observed malformations. Neither the potential of OTA to cause malformations in humans nor its teratogeni...

The teratogenic effect of rubella virus in humans has now been well documented (Ingalls, Plotkin, Meyer & Parkman, 1967) and virus isolation studies have suggested that rubella virus causes embryopathy by actually infecting the cells of the developing foetus (Alford, Neva & Weller, 1964). However, a laboratory animal model is required for controlled studies of the teratogenic activity of rubell...

In a retrospective study to compare the drug consumption during pregnancy of mothers of infants with congenital abnormalities and of those without, over 97% of 1,369 mothers took prescribed drugs and 65% self-administered drugs. Significantly more mothers of infants with congenital abnormalities took aspirin, antacids, dextroamphetamine, phenobarbitone, sodium amytal, other barbiturates, cough ...