Sepsis is a life-threatening organ dysfunction caused by disturbed response to infection. The development of sepsis preceded Systemic Inflammatory Response Syndrome (SIRS), which the overall inflammatory body severe lesion. role opportunistic pathogens in CER and may be considered proven, but value intestinal microbiome remains underestimated. survey systematized data on cell wall or membrane c...

Sepsis and its related syndromes represent potentially devastating illnesses, estimated to account for 1% of all hospital admissions and for 100 000 deaths per annum in the U.S.A. alone. Although sepsis is defined as the systemic response to infection, an infective organism is found in fewer than 50% of cases. It is therefore increasingly recognised that sepsis represents only one example of a ...

the concepts of SIRS and CARS still exist, although the notion that CARS represents a reaction to SIRS has been challenged [3, 4] . In this theme issue of the Journal of Innate Immunity, current knowledge of several aspects of the SIRS and CARS concepts are reviewed in 7 articles; the issue is completed by 3 original articles about these topics. Kumpf and Schumann [5] summarize data on genetic ...

DataSynthesis: Current evidence indicates that the early systemic inflammatory response syndrome observed after major surgery that is characterized by proinflammatory cytokine release, microcirculatory disturbance, and cell-mediated immune dysfunction is followed by a compensatory anti-inflammatory response syndrome, which predisposes the patient to opportunistic infection, multiple organ dysfu...

Inflammation of pancreatic parenchyma is said to be pancreatitis. It can be acute, presenting as emergency with short history or chronic as a continuation of acute with a long history. Autodigestion is responsible for pancreatitis on background of premature activation of pancreatic enzymes within the pancreas. Acute Pancreatitis is acute inflammation of the pancrease which can be mild to modera...

OBJECTIVES To compare serum concentrations of homocysteine in healthy dogs and those fitting the criteria for systemic inflammatory response syndrome and to compare these values to commonly measured B-vitamins. METHODS Study dogs were classified into non-infectious systemic inflammatory response syndrome or sepsis groups and blood was drawn on Day 1 of the patient's hospitalisation for measur...