17a-hydroxy-4-pregnen-3-one (17aP) hormone is a precursor of other steroid hormones and radioimmunoassay has already been used to measure it, but a simple and rapid "Enzyme Linked Immunosorbant Assay" (ELISA) is described and validated here. A general procedure for prepara-tion of the acetylcholinesterase labelled steroid is described, which is applicable to any steroid. Use of acetyl...

17a-hydroxy-4-pregnen-3-one (17aP) hormone is a precursor of other steroid hormones and radioimmunoassay has already been used to measure it, but a simple and rapid "Enzyme Linked Immunosorbant Assay" (ELISA) is described and validated here. A general procedure for prepara-tion of the acetylcholinesterase labelled steroid is described, which is applicable to any steroid. Use of acetyl...

testosterone level was determined in six different populations of iran using saliva steroid assay. significant difference was observed in morning and afternoon testosterone level of the same individual (p>0.00l) significant difference was also noticed among different regions studied (p>0.00 1). comparisons between alcoholics and nonalcoholic as well as smokers and nonsmokers showed significant ...

introduction: sandfish (holothuria scabra) is a marine species generally sold as a raw material that has been dried even though the meat contains steroid hormone with high economic value, which has the potential to become a source of safe natural steroid hormone. this study was aimed to look at the potency of sandfish as an anti-aging for menopausal women. sandfish could become a source of natu...

BACKGROUND Treatments for acute ischemic stroke have evolved as knowledge about the pathophysiology of ischemic brain injury has advanced. Treatment strategies under development are aimed at offering neuroprotection acutely after focal cerebral ischemic injury, but delayed initiation of therapy may reduce efficacy. Pretreatment before ischemia begins could offer distinct advantages in patient g...

objective(s) previous studies have demonstrated that pretreatment with alpha-tocotrienol (a-tct) can reduce ischemic damage in mice following middle cerebral artery (mca) occlusion. it is also reported to decrease stroke- dependent brain tissue damage in 12-lox-deficient mice and spontaneously hypertensive rats. in the present study, the neuroprotective effects of a-tct and rosiglitazone (rgz) ...

Abstract Neurodevelopmental and psychosocial impairments negatively impact health-related quality of life for survivors with CHD complicate the transition to independent adulthood. Risk neurodevelopmental is influenced by a complex interplay among genetic, foetal, surgical, perioperative, family, social factors, requiring multi-pronged approach neuroprotection intervention. To ensure future res...

Zuckerkandl’s organ (ZK) is an extra adrenal para-ganglion and has the ability to express glial cell line derived neurotrophic factor (GDNF) and transforming growth factor (TGF). It is also a source of dopamine and norepinephrine. In the present study, the neuroprotective and restorative potential of ZK was studied by transplanting it into the striatum of adult rats either before or after the i...