The present studies were designed to examine the effects of ribavirin (1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide), a broad-spectrum antiviral agent, on the generation of murine antibody responses in vitro. Whereas primary and secondary sheep erythrocyte-specific, plaque-forming cell responses by normal murine spleen cells were enhanced by low concentrations of ribavirin (1 microgram p...

wandering spleen, defined as a spleen without its usual peritoneal attachments, is a rare entity. we report a 34-year-old woman with acute abdomen due to torsion of the long vascular pedicle of a wandering spleen, displaced in the abdominal cavity, and infarction of the spleen. wandering spleen was diagnosed by ultrasound and computed tomography (ct) scan, and was managed by splenectomy in this...

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conclusions in conclusion, we recommend that laparoscopic spleen preserving procedures should be preferred for hydatid spleen when conditions are favorable and enough precautions are taken to prevent spillage. we suggest the use of aspirator for giving the scolicidal agent and favor the albendazole as an adjuvant therapy to prevent its recurrence. introduction cystic lesions of spleen are rare....

BACKGROUND: Considering widely administration of methylphenidate and also its immunosuppressive effects on different organs, importance of related microscopic studies is obvious. OBJECTIVES: Determining histological effects of methylphenidate on adrenal glands and lymphatic organs in mice. METHODS: A total number of 30 adult male Balb/C mice were provided, weighed and divided into one control a...

Murine spleen cells generate nonspecific cytotoxic cells, referred to as natural killer (NK) cells, within 4 d of incubation in Mishell-Dutton cultures. This NK cell type does not arise in cultures of BALB/c.nu spleen cells or in cultures of T-cell depleted C57BL/6 spleen cells, indicating that its activation depends on T cells. Another type of NK cells is induced by tumor necrosis serum in mur...

The ability of lymphoid cells from immunized animals to regulate the response of naive B ceils to the immunizing hapten was studied. Mice were immunized with trinitrophenylated (TNP) bovine gamma globulin (BGG) in complete Freund's adjuvant, and their spleen cells were examined in vivo and in vitro for the presence of specific inhibitory activity. This activity was found to peak 1 wk after immu...

abstract introduction: primary dysmenorrhea is common in women during reproductive age. objective: this study aimed to determine the effect of acupressure on sixth spleen point (sp6) on relief of primary dysmenorrhea. methods: this study is a clinical trial. students with primary dysmenorrheal living in dormitory were studied during three menstrual cycles. pain intensity was measured on the fir...

conclusions here, we discuss the pathogenesis of the rare entity of splenic hydatid cysts and the various treatment options available. background hydatid cyst, a zoonosis caused by echinococcus granulosus, is the only recognized parasitic cysts of the spleen and is known to be at least twice as common as the non-parasitic variety. case presentation a 35 year old woman presented with a one-year ...