Lesions to left frontal cortex in humans produce speech production impairments (nonfluent aphasia). These impairments vary from subject to subject and performance on certain speech production tasks can be relatively preserved in some patients. A possible explanation for preservation of function under these circumstances is that areas outside left prefrontal cortex are used to compensate for the...

The effects of classroom noise and background speech on speech perception, measured by word-to-picture matching, and listening comprehension, measured by execution of oral instructions, were assessed in first- and third-grade children and adults in a classroom-like setting. For speech perception, in addition to noise, reverberation time (RT) was varied by conducting the experiment in two virtua...

BACKGROUND Persisting neurological and cognitive impairments are common after cerebral malaria. Although risk factors for gross deficits on discharge have been described, few studies have examined those associated with persistent impairments. METHODS The risk factors for impairments following cerebral malaria were determined by examining hospital records of 143 children aged 6-9 years, previo...

Language is a characteristic feature of human communication. Several familial language impairments have been identified, and candidate genes for language impairments already isolated. Studies comparing expression patterns of these genes in human brain are necessary to further understanding of these genes. However, it is difficult to examine gene expression in human brain. In this study, we used...

Specific Language Impairment (SLI) is observed in children who fail to acquire age-appropriate language skills but otherwise appear to be developing normally. There are two main hypotheses about the nature of these impairments. One assumes that they reflect impairments in the child's innate knowledge of grammar. The other is that they derive from information-processing deficits that interfere w...

This study evaluated a computerised program for training spelling in 8to 13-yearolds with receptive language impairments. The training program involved children typing words corresponding to pictured items whose names were spoken. If the child made an error or requested help, the program gave phonological and orthographic cues to build up the word’s spelling. Eleven children received this train...

This paper addresses the impact of telephone transmission channels on automatic speech recognition (ASR) performance. A real-time simulation model is described and implemented, which allows impairments that are encountered in traditional as well as modern (mobile, IP-based) networks to be flexibly and efficiently generated. The model is based on input parameters which are known to telephone net...