Testosterone has been hypothesized to modulate the trade-off between mating and parenting effort in males. Indeed, evidence from humans and other pair-bonded species suggests that fathers and men in committed relationships have lower testosterone levels than single men and men with no children. To date, only one published study has examined testosterone in relation to motherhood, finding that m...

The TMPRSS2 protein is an entry pathway for SARS-CoV-2, its expression up-regulated by testosterone. Men have 7 to 8 times higher serum testosterone than women. We propose that patients hospitalized with COVID-19, levels of testosterone, worse outcomes those lower levels.

background: physical exercise is known to be a stressor stimulus that leads to reproductive disruption.objective: the aim of this study was to evaluate the effect of forced swimming on the uterus and ovaries in mice.materials and methods: adult mice (n=24) were divided into the following threegroups: a, control; b, swimming in water (10popc); and c, swimming in water (23popc).swimmers swam for ...

Bone may contain an intraskeletal reservoir of sex steroids that is capable of producing biological effects. The purposes of these experiments were to 1) establish and validate methods to extract and measure intraskeletal sex hormones, 2) compare serum and intraskeletal sex hormone abundance, and 3) determine the impact of testosterone-enanthate administration and orchiectomy on intraskeletal s...

Introduction: Although males and females have the same prevalence of COVID-19, a variation in severity symptoms between has been observed. We hypothesize that this can partly be explained by effect androgens on infectious activity SARS-Cov2 virus.
 Aims: This study investigated sex two androgenic drugs testosterone oxandrolone mRNA expression several entry genes: angiotensin-converting enz...

Background: Although effects of trace elements on secretion of sex steroids and insulin have been studied, the effects of these hormones on serum level of trace elements have been rarely investigated. The aim of the present study was to evaluate the effect of testosterone and finasteride administration and castration on serum levels of testosterone, insulin, zinc and chromium. Methods: Male adu...

Objective Spinal cord injury (SCI) causes infertility in male patients through erectile dysfunction, ejaculatory dysfunction, semen and hormone abnormalities. Oxidative stress (OS) is involved in poor semen quality and subsequent infertility in males with SCI. The aim of this study is to examine the effects of SCI on the level of testosterone hormone. MaterialsAndMethods In this experimental st...

A fully automated direct assay of testosterone has been developed for the Ciba Corning ACS:180 immunoassay system. We have evaluated this method and compared specimen results with those from the Diagnostic Products Corp. (DPC) and Medgenix direct assays and an in-house extraction assay. Accuracy of the method was assessed by measuring GC-MS-targeted serum pools. Within-assay im- precision was <...

the effects of exposure to chemical weapons containing sulfur mustards on the serum levels of total and free testosterone. gonadotropins and prolactin was investigated in young iranian men. in the first five weeks after injury both serum total and free testosterone were significantly decreased as compared to control values. three of 13 men had total testosterone below 300 ng/dl and two of six h...