An enzyme-linked immunosorbent assay was used to study the subclass distribution of rubella virus-specific immunoglobulin G (IgG) in 97 serum samples from healthy donors and from patients with recent or remote rubella infections. Plastic beads coated with rubella antigen were incubated with test serum and then with monoclonal antibodies to the four human subclass of IgG. Rubella virus-specific ...

Introduction. Rubella infection has the potential of causing severe fetal birth defects collectively called congenital rubella syndrome (CRS) if the mother is infected early in pregnancy. However, little is known about rubella and CRS epidemiology in Nigeria and rubella vaccines are still not part of routine childhood immunization in Nigeria. Methods. Analysis of confirmed cases of rubella in A...

In 1985 a patient was described whose persistent polyarthritis was found to be aetiologically linked to rubella virus infection through the detection of repeated maximal synovial lymphocyte proliferative responses to rubella virus antigen and by isolation of rubella virus from her synovium. Follow up over the succeeding seven years has shown continuing chronic polyarthritis and persistent synov...

rubella or german measles is a mild contagious disease in non-pregnant women, but in pregnant affected mother’s possibility of fetus infection in the first twelve weeks of gestation is 80%. between 13-14 weeks of gestation is 54% and by the end of the second trimester is 25%. if fetus gets infected severe anomalies will progress. at present no vaccination against rubella is begin envisaged by t...

background:infection of mothers with rubella virusduring pregnancy can be serious; if the mother is infected within the first 20 weeks of pregnancy she is likely to have miscarriage, stillbirth, or baby with congenital rubella syndrome. this study was carried out to define rubella virusseroprevalence in pregnancy in osogbo, nigeria. methods:this study is a cross-sectional sero-survey of rubella...

BACKGROUND Congenital rubella syndrome (CRS) can be prevented with appropriate vaccination programs. The prevalence rates of rubella and CRS in Iran are unknown; therefore, the risk of exposure in pregnant women is not clear. The prevalence of CRS in the pre-vaccine period can be estimated by evaluating the proportion of children in the population with sensorineural hearing loss attributable to...

BACKGROUND Sero-positivity rates of the rubella virus among pregnant women vary widely throughout the world. In Tanzania, rubella vaccination is not included in the national immunization schedule and there is therefore no antenatal screening for this viral disease. So far, there are no reports on the sero-prevalence of rubella among pregnant women in Tanzania. As a result, this study was undert...

BACKGROUND Elimination of congenital rubella syndrome depends not only on effective childhood immunization but also on the identification and immunization of rubella susceptible women. We assessed rubella susceptibility among pregnant women and evaluated the adherence and response to postpartum immunization with measles, mumps and rubella (MMR) vaccine. METHODS Cross-sectional study of women ...

Rubella is a contagious viral infection that affects pregnant women during early pregnancy which leads to the infection of a developing fetus, causing congenital rubella syndrome (CRS). Although rare in many industrialized countries, because of the success of vaccination programs, rubella continued to occur in many developing countries with no vaccination program. Rubella immunization rates are...

This study was conducted to assess clinical and laboratory screening for suspected congenital rubella syndrome (CRS) and to evaluate the efficacy of reporting of CRS cases at the Children’s Hospital and the Institute of Child Health. A total of 100 infants suspected of having rubella infection were included in the study. Rubella titer was used as an indicator. Enzyme linked immunosorbent assay ...