aim : the aim of this study is to estimate gastric cancer (gc) mortality rate for iranian population, using bayesian approach in order to revise the existing classification which is thought to be a misclassification. background : gastric cancer (gc) is an important cause of mortality among many other types of cancer. data on cancer mortality can be used to guide policy makers in order to setup ...

background: although several in vitro and animal studies have suggested that isoflavones might exert inhibitory effects on gastric carcinogenesis, epidemiologic studies have reported inconclusive results in this field. the aim of this brief review was to investigate whether such an association exists among dietary isoflavones and gastric cancer incidence, prevention, and mortality in epidemiolo...

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PURPOSE (18)F-fluorodeoxyglucose positron emission tomography/computed tomography ((18)F-FDG PET/CT) scans are frequently performed for the screening or staging of malignant tumors. This study aimed to assess the usefulness of (18)F-FDG PET/CT in detection of gastric cancer recurrence after curative gastrectomy. MATERIALS AND METHODS Eighty nine patients who had undergone curative gastrectomy...

PURPOSE There are few studies that have focused on the predictors of recurrence after gastrectomy for gastric carcinoma. This study analyzed the patients who died of recurrent gastric carcinoma and we attempted to clarify the clinicopathologic factors that are associated with the timing of recurrence. MATERIALS AND METHODS From June 1992 to March 2009, 1,795 patients underwent curative gastri...

background: it is presumed that gastric cancer has several etiologies. first-degree relatives of patients with gastric cancer are suggested to be at higher risk compared to others. this is the first study aimed at estimating this risk, using meta-analysis of case-control studies. materials and methods: all records prior to february 2008 in pubmed and embase were searched for case-control studie...

objective(s):mirnas have been proposed to be key regulators of tumorigenesis, progression and metastasis. however, their effect and prognostic value in gastric cancer is still poorly known. materials and methods: gastric cancer cell lines were cultured. tissue samples obtained from 36 gastric cancer patients were used for quantitative real-time pcr (qrt-pcr) analysis. the tissue microarrays (tm...

Advanced or metastatic gastric cancer, which is one of the most common malignancies in Korea, is difficult to cure by surgery alone and generally requires combination chemotherapy. Paclitaxel is active against gastric cancer and when combined with 5-fluorouracil/leucovorin and/or cisplatin is effective in the treatment of gastric cancer. We attempted to determine the effect and safety with the ...

background: germline mutations in mmr genes are reported to be present in more than 70% of hnpcc cases. but, there is a paucity of data regarding the importance of defect of mmr system in the gastric cancer in general. so, in this study, we used ihc stain formlh1,msh2, pms2 andmsh6 to reveal profile ofmmr expression in patients with gastric cancer. materials and methods: this study was performe...