نتایج جستجو برای: receptor pharmacology
تعداد نتایج: 615995 فیلتر نتایج به سال:
G protein-coupled receptor (GPCR)-Galpha fusion proteins were first characterized more than 10 years ago as a strategy for studying receptor-G protein signaling. A large number of studies have used this approach to characterize receptor coupling to members of the Gs, Gi, and Gq families of Galpha subunits, but this strategy has not been widely used to study Galpha12 and Galpha13. As described i...
The G protein-coupled estrogen receptor (GPER, nomenclature as agreed by the NC-IUPHAR Subcommittee on [26]) was identified following observations of estrogen-evoked cyclic AMP signalling in breast cancer cells [2], which mirrored differential expression an orphan 7-transmembrane GPR30 [6]. There are both cell-surface and intracellular GPER [29, 34]. Selective agonist/ antagonists for have been...
A1 Neurokinin 1 receptor antagonism promotes active stress coping via enhanced septal 5-HT transmission Georg M Singewald, Karl Ebner, Nigel Whittle, Francesco Ferraguti and Nicolas Singewald Department of Pharmacology and Toxicology, Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Austria Department of Pharmacology, Medical University of Innsbruck, Austria E-Mail: n...
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