OBJECTIVES The aim of this study was to survey the available literature on psychological development of panic disorder with or without agoraphobia [PD(A)] and its relationship with the neurobiology and the treatment of panic. METHODS Both a computerized (PubMed) and a manual search of the literature were performed. Only English papers published in peer-reviewed journals and referring to PD(A)...

Up to 29% of patients with epilepsy report "prodromal" sensations more than 30 minutes prior to seizures. We developed and implemented an objective methodology to prospectively assess the sensitivity and specificity of these subjective experiences using personal digital assistants (PDAs). The key property, in contrast to paper-based diaries, is the internal recording of the patient's entering t...

PURPOSE The aim of this study was to assess how frequently prodromes occur in an adult patient group from a tertiary referral epilepsy centre and to investigate the EEG changes during the prodromes. METHODS 578 consecutive patients were interviewed on subjective phenomena, experiences heralding the seizures, for at least 30min before the start of the seizure. EEGs were recorded during the pro...

Analysis of electroencephalographic signals and several brain imaging studies suggest that a preictal state precedes the onset of seizures. In this study, we used phenomenological strategies to detect modifications in patients' experience before their seizures. We observed that patients with partial epilepsy feeling an aura (n=9) frequently experienced prodromes (n=6). Prodromes were subtle pre...

In the last decade, there has been an increasing interest in cognitive alterations during the early course of schizophrenia. From a clinical perspective, a better understanding of cognitive functioning in putative at-risk states for schizophrenia is essential for developing optimal early intervention models. Two approaches have more recently been combined to assess the entire course of the init...

Ischemic pancolitis should be considered in the differential diagnosis of ischemic colitis, particularly in patients with a hypotensive prodrome. Although indications for surgery do not differ from those of segmental ischemia, vigilant examination of the entire colon at laparotomy as well as cautious preor intraoperative colonoscopy are necessary in order to recognize the diffuse nature of the ...

Current literature suggests that tendonitis of the extensor pollicis longus (EPL) is a rare condition that has a high rate of progression to rupture. This study documents the prodrome of impending EPL rupture in patients with prior nondisplaced distal radial fracture. A retrospective study identified patients with EPL tendonitis or tendon rupture. Seven patients (6 females and 1 male) had susta...