Astrin is a mitotic spindle-associated protein required for the correct alignment of all chromosomes at the metaphase plate. Astrin depletion delays chromosome alignment and causes the loss of normal spindle architecture and sister chromatid cohesion before anaphase onset. Here we describe an astrin complex containing kinastrin/SKAP, a novel kinetochore and mitotic spindle protein, and three mi...

BACKGROUND Peters Plus syndrome (MIM 261540) is a rare autosomal recessive condition characterized by ocular defects (typically Peters anomaly) and other systemic major/minor abnormalities. Mutations in the B3GALTL gene encoding the β-1,3-glucosyltransferase have been found in virtually all patients with typical Peters Plus syndrome. CASE PRESENTATION We report here a female patient with seve...

The aim of this study was to determine the effects of vasopressin V 1 receptor antagonism on regional hemodynamics in spontaneously hypertensive rats (SHR/Izm). Changes in blood flow in the superior mesenteric artery or terminal aorta were measured in rats with a chronically implanted electromagnetic flowmeter. The combination of a non-hypotensive hemorrhage (0.3 ml/100 g weight) and ganglionic...

to evaluate the enhancement effect of berberis vulgaris var. integerrima seeds on the antibacterial activity of cephalexin and ceftizoxime against staphylococcus aureus and escherichia coli ethanol extract of the seeds were prepared. disk diffusion and broth dilution methods were used to determine the antibacterial activity of two cephalosporins in the absence and presence of the extract and it...

PURPOSE Corneal allografts placed orthotopically induce a unique and unusual response in recipient mice. More orthotopic corneal allografts are accepted indefinitely than similar skin allografts. Of the rejected corneal grafts, class I major histocompatibility complex (MHC)-incompatible grafts are rejected less frequently than grafts that express only minor histocompatibility complex (minor H) ...

In this note we investigate some matroid minor structure results. In particular, we present sufficient conditions, in terms of triangles, for a matroid to have either U2,4 or F7 or M(K5) as a minor.