the present investigation aims at assessing the hepatoprotective effect of triterpene fraction isolated from the stem bark of wrightia tinctoria (containing lupeol, b -amyrin and b -sitosterol) on ccl 4 -induced hepatotoxicity in the rat. ccl 4 (1.5 mg/kg, i.p) is a potent hepatotoxic agent which causes peroxidative degeneration of membrane lipids with the potential outcome of fatty degeneratio...

background: recent studies demonstrated that resveratrol has many therapeutic effects on liver disorders. resveratrol significantly increased survival after liver transplantation, decreased fat deposition, necrosis, and apoptosis which induced by ischemia in wistar rats. it provided liver protection against chemical, cholestatic, and alcohol injury. resveratrol can improve glucose metabolism an...

HYPOTHESIS Perioperative carcinoembryonic antigen (CEA) blood level is a predictor of outcome after resection of colorectal liver metastases (CLMs). DESIGN Prospective clinical study. SETTING Department of digestive surgery and transplantation. PATIENTS Between January 1, 2000, and December 31, 2004, CEA levels were routinely measured 1 week before and 6 weeks after CLM resection in 213 p...

We describe a 48-year-old man with cholecystolithiasis whose preoperative magnetic resonance cholangiopancreatography (MRCP) scan showed that the right accessory hepatic duct branching from the cystic duct dominated an anterior segment of the right hepatic lobe. We observed the right accessory hepatic duct using intraoperative cholangiography, and we were able to perform laparoscopic cholecyste...

the most common cardiovascular surgery in the world and iran as well, is cabg. one of the most important post-operative complication of this operation, that increase morbidity and mortality, is peri-operative mi. incidence of peri-operative mi in cabg operations is between 2.5 to 5.5%. in this study we determined the prevalence and incremental risk factors of peri-operative mi in 300 consequati...

background: statins (3-hydroxy-3-methylglutarylcoenzyme-a (hmg-coa) reductase inhibitors) decrease cardiovascular mortality and morbidity. this article reviews the role of perioperative statins in non cardiac surgery. methods: a literature review was done on all english published articles till february 2015 about this subject using pubmed. then the reference list of relevant articles was review...

A main goal of cancer immunology research is the formation of Ag-specific memory T cell immunity capable of activation upon tumor re-encounter. The requirements necessary to overcome the inhibitory signals present in the tumor microenvironment and form such memory T cell responses are unknown. In contrast to previous studies targeting tumors expressing highly immunogenic model Ags, we demonstra...

Preoperative cardiac assessment has become an integral part of contemporary anesthesia practice. Simple clinical markers can identify high-risk patients, but the question of how to reduce cardiac complications among high-risk patients has been controversial. Good quality randomized controlled trials have showed that neither preoperative coronary revascularization nor the placement of pulmonary ...

A retrospective analysis of clinical and pathological factors was performed on 132 surgical cases with solitary-nodule type HCC in our hospital. The overall cancer-free survival rates after 1, 3 and 5 years were 82.2%, 42.3% and 26.5%, respectively. With univariate analysis, the significant prognostic factors for survival were tumor size, cancer cell infiltration of the fibrous capsule of the t...