hour 23 (rabeprazole 100% vs. omeprazole 74%,. P < 0.02). Conclusions: Rabeprazole, 20 mg, demonstrated superior control of peptone mealstimulated . Comparison of rabeprazole 20 mg vs. omeprazole 20 mg in the treatment of. . new PPIs rabeprazole, pantoprazole and lansoprazole compared to omeprazole. Nov 1, 2007. Four studies of pantoprazole (Protonix) 40 mg versus omeprazole. Two studies of rab...

BACKGROUND Despite frequent clinical use, information about the pharmacokinetics and efficacy of pantoprazole in camelids is not available. OBJECTIVES To examine the pharmacokinetics of both IV and SC pantoprazole and to determine whether pantoprazole administration would increase 3rd compartment pH in alpacas. ANIMALS Six healthy adult alpacas. METHODS Alpacas were fitted with a 3rd comp...

introduction: atrial arrhythmia is a common complication in patients with gastro esophageal reflux disease (gerd). the treatment of palpitation is relatively problematic in these patients, especially if there is not enough evidence of cardiovascular or systemic diseases. the esophagus is in close proximity to the left atrium posterior wall. hypothetically, locally released cytokines from esopha...

objective(s):pantoprazole, is a proton pump inhibitor (ppi) prescribed for the treatment of upper gastrointestinal disorders, which in high doses has been suggested to decrease calcium absorption leading to hypocalcaemia and therefore osteoporosis. the aim of this study was to assess whether pantoprazol, could alter the rate of orthodontic tooth movement (otm) in rats. materials and methods: a ...

BACKGROUND Until now there has been no study that directly compares the effect of lansoprazole and pantoprazole administered intravenously on intragastric acidity. The aim of this study is to compare the effect of lansoprazole (30 mg) and pantoprazole (40 mg) administered intravenously on gastric acidity. MATERIAL/METHODS Helicobacter pylori-negative healthy volunteers were recruited in this ...

BACKGROUND AND AIM Following successful endoscopic therapy in patients with peptic ulcer bleeding, rebleeding occurs in 20% of patients. Rebleeding remains the most important determinant of poor prognosis. We investigated whether or not administration of pantoprazole infusion would improve the outcome in ulcer bleeding following successful endoscopic therapy. METHODS In this double-blind, pla...

Elective esophageal variceal ligation (EVL) is performed to decrease the risk of variceal hemorrhage. Side effects of EVL include hemorrhage, chest pain, dysphagia, and odynophagia. Because gastric acid may exacerbate postbanding ulcers and delay healing, proton pump inhibition may decrease side effects associated with EVL. The aim of this study was to assess the efficacy of pantoprazole, a pro...

Drug-plasma protein binding is one of the many factors which influence bioavailability of a drug. Efficacy, distribution and elimination of a drug can be affected by the reversible binding of the drug to plasma proteins, such as albumin and acid glycoprotein. The purpose of the study was to study the relative in vitro protein binding characteristics of various drugs like diclofenac sodium, pant...

Simple, sensitive and accurate methods for determination of four drugs viz., Ciprofloxacin, Pantoprazole Sodium Sesquihydrate, Atrovastatin Calcium and Rosuvastine Calcium have been developed. The methods depend upon the oxidation of the drug by a known excess Ceric Ammonium Sulphate in sulphuric acid medium and subsequent determination of unreacted Ce (IV) using Amaranth dye. The methods have ...

BACKGROUND Recent pharmacodynamic and retrospective clinical analyses have suggested that proton pump inhibitors (PPIs) may modify the antiplatelet effects of clopidogrel bisulfate. METHODS We conducted a retrospective cohort study of persons enrolled in a multistate health insurance plan with commercial and Medicare clients to evaluate adverse clinical outcomes in patients using clopidogrel ...