The face distinguishes one person from another. Postnatal orofacial tissues harbor rare cells that exhibit stem cell properties. Despite unmet clinical needs for reconstruction of tissues lost in congenital anomalies, infections, trauma, or tumor resection, how orofacial stem/progenitor cells contribute to tissue development, pathogenesis, and regeneration is largely obscure. This perspective a...

orofacial granulomatosis(ofg) is a granulomatous disease of the orofacial region which appears usually as a persistent and/or recurrent labial soft tissues swelling in the orofacial region and is characterized histologically by a granulomatous inflammation. ofg may cause significant cosmetic and functional problems but can be prevented if the disease is diagnosed early and promptly treated. the...

We describe a patient with orofacial pain as the presenting symptom caused by a mandibular metastasis from a previously undiagnosed cancer of the prostate. This possibility should be considered in the differential diagnosis of male patients presenting with orofacial pain.

Objective: The purpose of this editorial is to alert otolaryngologists to Orofacial Myofunctional Disorders (OMDs) and their primary causes of airway interferences and allergies. An understanding of the variety of OMDs should facilitate improved communications between otolaryngologists and orofacial myologists. Method: OMDs are identified, and the dental alignment and other consequences of OMDs...

BACKGROUND Temporomandibular joint (TMJ) inflammation in patients with juvenile idiopathic arthritis (JIA) can lead to orofacial pain and malfunction of the TMJ. Intra-articular corticosteroid injections (IACI) have been suggested as a treatment modality against TMJ arthritis-related orofacial signs and symptoms. However, knowledge of the effect-durability of these injections remains unanswered...

in this study, the effects of subcutaneous (sc) injection of pilocarpine (a cholinomimetic agent) and atropine (a muscarinic receptors antagonist) were investigated on a tonic model of orofacial pain in rats. the contribution of the endogenous analgesic opioid system was assessed using naloxone (an opioid receptors antagonist). tonic orofacial pain was induced by sc injection of a diluted forma...

OBJECTIVES The aim of the current study was to investigate whether there was a relationship between a history of third molar removal and the prevalence of orofacial pain in a sample of the general population. MATERIAL AND METHODS A survey was conducted in South East Cheshire, United Kingdom (81% participation rate). Information was collected using postal questionnaires (n = 1510) and dental r...

Orofacial granulomatosis is defined by permanent or recurrent swelling of orofacial tissues with different multiform and multifocal clinical patterns. An 11-year old boy presented with a 2-month history of mucosa enlargement. Intraoral examination revealed an erythematous, polylobulated, exophytic lesion with a smooth surface located in retromolar mucosa, non-tender and non-infiltratated to pal...

background: major -thalassemia is the most common monogenic known disorder in iran and about 15000 persons are af fected. the purpose of this study was to evaluate the prevalence of orofacial complications. methods: in this cross-sectional study during 2003-2004, 300 patients with major -thalassemia referring to 8 hospitals for routine examinations, blood infusion and treatment in cities of teh...