Norplant® is the brand name of the world's first registered subdermal hormonal contraceptive implant, developed by the laboratories of the Population Council, an international organisation working in the area of fertility and population growth. The article revisits the trajectory of this contraceptive in Brazil from its arrival through clinical trials to its eventual ban in 1986 by the Brazilia...

We assessed the influence of hormonal (oral, injectable, or levonorgestrel [Norplant, Wyeth-Ayerst, Philadelphia, PA]) and barrier methods of contraception on the risk of cervical squamous intraepithelial lesions (SIL), while adjusting for high-risk (HR) HPV infection. Subjects were women receiving family planning services through the state health department clinics from 1995 to 1998. We select...

PURPOSE Men's attitudes toward contraceptives are an understudied area, even though many men participate in contraceptive decision making. The purpose of this study was to examine attitudes and perceptions regarding a selection of contraceptive methods among a national sample of African Americans, with a particular focus on gender differences. METHODS Data come from a telephone survey of Afri...

In response to the need of some women for long-acting, effective and safe contraceptives, the scientific community developed non-biodegradable progestational subdermal implants that act by making the cervical mucus viscous, with ovulation inhibition and thinning of the endometrial lining. The contraceptive protection is within 24 hours and the cumulative failure rate is low. Contraceptive impla...

With the purpose of measuring the duration of the functional life-span (FLS) of the anovulatory follicle in women under continuous low-dose progestogen treatment, the oestradiol curve of Norplant implant users was retrospectively analysed. From all the data collected during the previous 5 years at the Department of Biomedical Research at the Family Planning Clinic of Profamilia, Santo Domingo, ...