BACKGROUND Gastroesophageal reflux is common among patients with asthma but often causes mild or no symptoms. It is not known whether treatment of gastroesophageal reflux with proton-pump inhibitors in patients who have poorly controlled asthma without symptoms of gastroesophageal reflux can substantially improve asthma control. METHODS In a parallel-group, double-blind trial, we randomly ass...

OBJECTIVE Sleeve gastrectomy is the fastest growing surgical procedure to treat obesity in the world but it may cause or worsen gastroesophageal reflux disease. This article originally aimed to describe the addition of anti-reflux procedures (removal of periesophageal fats pads, hiatoplasty, a small plication and fixation of the gastric remnant in position) to the usual sleeve gastrectomy and t...

UNLABELLED The aim of this study was to use gastroesophageal and pulmonary scintigraphy to evaluate the prevalence of gastroesophageal reflux and airway involvement among patients with posterior laryngitis. METHODS The study included a total of 201 patients (131 females, 70 males; age range, 15-77 y; mean age +/- SD, 49 +/- 16 y). All patients had posterior laryngitis documented by laryngosco...

BACKGROUND/AIMS Detailed characterization of the ultrastructural morphology of intercellular space in gastroesophageal reflux disease has not been fully studied. We aimed to investigate whether subtle alteration in intercellular space structure and tight junction proteins might differ among patients with gastroesophageal reflux disease. METHODS Esophageal biopsies at 5 cm above the gastroesop...

The mechanical force relationships that distinguish normal from chronic reflux at sphincter opening are poorly understood and difficult to measure in vivo. Our aim was to apply physics-based computer simulations to determine mechanical pathogenesis of gastroesophageal reflux. A mathematical model of the gastroesophageal segment (GES) was developed, incorporating the primary anatomical and physi...

Background: Gastroesophageal reflux is a common problem in children, and (Gastroesophageal reflux disease) GERD comprises its objective pathologic sequelae, but the term has also been used more recently to denote symptoms affecting quality of life. The Clinical presentation is very variable. It causes mortality and morbidity without appropriate treatment plan. Objective: We are going to evaluat...

Gastroesophageal reflux induced cough is a common cause of chronic cough, and proton pump inhibitors are a standard therapy. However, the patients unresponsive to the standard therapy are difficult to treat and remain a challenge to doctors. Here, we summarized the experience of successful resolution of refractory chronic cough due to gastroesophageal reflux with baclofen in three patients. It ...

background and aim: the purpose of present study was to evaluate endoscopic features, prevalence of complications, response to treatment and necessity of the endoscopy in the patients with gastroesophageal reflux disease (gerd) symptoms. materials and methods: we selected the patients with gerd symptoms in amiralmomenin hospital from 1381 to 1382. 277 cases were tested in this study. group 1, (...

asthma and  gastroesophageal reflux disease (gerd)  are two  common  problems  in pregnancy and they affect pregnancy in several ways. in this study, we aimed to evaluate gerd and asthma in pregnant women who referred for prenatal care visits. one-hundred  and seventy three  pregnant  women with a complaint of  dyspnea were included in the study. a questionnaire was filled and lung function tes...