The principal findings of a study for further evaluating paraffin baiting as a routine laboratory diagnostic procedure in the isolation of Nocardia asteroides, the etiological agent of nocardiosis, are reported.

<i>Nocardia</i> spp. are filamentous Actinobacteria of the order Corynebacteriales and mostly known for their ability to cause localized systemic infections in humans. However, onset progression nocardiosis is only poorly understood, particular mechanisms strain-specific presentations. Recent genome sequencing has revealed an extraordinary capacity production specialized small molec...

© 2017 Advanced Biomedical Research | Published by Wolters Kluwer Medknow Sir, Shirani et al. recently reported an article entitled, “Nocardial brain abscess in a patient with pulmonary alveolar proteinosis” (DOI: 10.4103/2277-9175.164004).[1] The genus Nocardia is a Gram-positive aerobic, partially acid-fast, and fi lamentous bacterium that causes nocardial infections (nocardiosis) in human. T...

Effect of cortisone administration on the pathogenicity of Nocardia asteroides, N. caviae, and N. brasiliensis for white mice has been investigated by using the intravenous route of inoculation. The observations indicated that the susceptibility of white mice to nocardiosis was enhanced by cortisone. Test strains of the three species of Nocardia caused a higher and more rapid mortality, as well...

We read with interest the recent article by Tendolkar et al. (5). We have been seeing and treating cases of Nocardia keratitis for a long time and have published our experiences previously (3, 4). We would like to share some of our observations on this condition for the benefit of JCM’s readers. Nocardia keratitis can occur in immunocompetent patients following minor trauma (3). While lagophtha...

1. Mamelak AN, Obana WG, Flaherty JF, Rosenblum ML. Nocardial brain abscess: Treatment strategies and factors influencing outcome. Neurosurgery 1994;35:622‐31. doi: 10.1227/00006123‐199410000‐00007. 2. Gendelman H, Rappaport J, Hickey W. The blood‐brain barrier: Defensive shield or a perpetrator of microbial invasion? J Neurovirol 1999;5:533‐7. doi: 10.3109/13550289909021283. 3. Wallace RJ Jr, ...

Nocardia, a branching, filamentous bacteria, is widely distributed in the environment and can cause human infection in immune-compromised hosts. Inhalation of Nocardia leads to pulmonary disease. Microbiology laboratory processed the clinical samples from patients with respiratory infections. Smears were prepared from the samples and were stained and cultured. Five cases were positive for Nocar...

lateral ventricle (Figure 2). The MRI scan showed an Introduction abscess and from a biopsy N. asteroides was isolated. Twenty-four hours later the abscess was excised, treatInfection from bacteria from the Nocardia class is ment with TMP-SMX was resumed and the cyclosporin seldom found in our country. They are opportunist dose was reduced. Throughout this period the patient infections that alm...

Nocardiosis is an uncommon bacterial gram-positive infection caused by aerobic actinomycetes in the genus Nocardia. Nocardiosis is typically regarded as an opportunistic infection with approximately two-thirds of infected patients being immunocompromised. In this case report we describe a 45-year-old female who presented with a right thigh abscess. She had been taking high-dose prednisolone and...

Nocardia farcinica is an emerging pathogen in immunocompromised hosts. Even though several species of Nocardia have been reported as causative pathogens of catheter-related blood stream infections (CRBSI), CRBSI caused by N. farcinica has not been reported. A 70-yr-old man with a tunneled central venous catheter (CVC) for home parenteral nutrition was admitted with fever for two days. Norcardia...