A method is described for the determination of nitrazepam and its reduced product in blood serum and urine. The metabolite, the reduced product, is the principal substance to be encountered in these fluids. A method is also described for the determination of librium (and the lactam) in urine.

GENERIC NAME PAGE Carbamazepine 378 Clobazam 381 Clonazepam 380 Clorazepate 381 Diazepam 383 Ethosuximide 381 Ethotoin 378 Felbamate 382 Fosphenytoin 383 Gabapentin 382 Levetiracetam 382 Lamotrigine 379 Lorazepam 380 GENERIC NAME PAGE Mephenytoin 378 Mephobarbital 381 Metharbital 381 Nitrazepam 381 Oxcarbazepine 379 Phenobarbital 381 Phenytoin 377 Primidone 381 Tiagabine 381 Topiramate 379 Valp...

OBJECTIVE To review the result of the infantile spasms' treatment with sodium valproate followed by nitrazepam or clonazepam. STUDY DESIGN Descriptive retrospective study. SETTING Srinagarind Hospital, Department of Pediatrics, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand. MATERIAL AND METHOD Twenty-four infantile spasms admitted between January 1994 and December 2003 we...

Data relating to the use of hypnotic medicines from a descriptive epidemiological study of drug use in 55 residential homes for elderly people were analysed. Of the 1888 residents included in the study, 435 (23.0%) were receiving a total of 448 hypnotic medicines. There was preferential prescribing of short-acting benzodiazepines but long-acting benzodiazepines represented 31.7% of all hypnotic...