Background: Nicotine is considered as one of the most agents in cigarette smoking and has side effects on many organs and body systems such as reproductive tract. Nicotine can induce sub fertility or infertility both in males and females. The aim of this study was to evaluate the proliferative activity of adult mouse male germ cells following treatment with different doses of nicotine. Material...

Background & Aims: Allergic diseases have increased in the last decade worldwide and researchers have been trying to introduce new strategies and drugs to treat these types of diseases. Nicotine shows anti-inflammatory properties and the studies have revealed that it can reduce the inflammation and the allergic responses. The mammalian target of rapamycin (mTOR) is a multifunctional protein kin...

Tobacco smoking and high-fat diet (HFD) independently impair short-term memory. E-cigarettes produce e-vapour containing flavourings nicotine. Here, we investigated whether inhalation interacts with HFD to affect memory neural integrity. Balb/c mice (7 weeks, male) were fed a (43% fat, 20 kJ/g) for 16 weeks. In the last 6 half of exposed tobacco-flavoured from nicotine-containing (18 mg/L) or n...

The purpose of this study was to explore the effects nicotine on activity Streptococcus mutans (S. mutans) in soft drinks. Regular drinks contain large proportions high-fructose corn syrup (HFCS), which increases S. resulting high-caries risk compared with sugar-free Nicotine use exhibits a strong correlation increased biofilm formation. chosen were (Coca-Cola Classic, Diet Coke, Coca-Cola Zero...

introduction: nicotine is the psychoactive substance responsible for establishing and maintaining smoking dependence. cyp2a6 is the primary enzyme that inactivates nicotine to cotinine .genetic variation in cyp2a6 accounts for some of the inter-individual variability in nicotine metabolism and has been indicated to influence smoking behavior and dependence. therefore, the aim of this study was ...

background: many psychiatric patients have nicotine and other substance dependence.   objective: to determine the prevalence of nicotine and opium dependence among psychiatric in-patients inkerman, a city in southwesterniran.   methods: three groups of psychiatric inpatients, chronic medical patients and a sample from local population, each including 400 subjects were selected.  nicotine depend...

objective(s) cigarette and nicotine enhances embryogenesis, fertility, pregnancy loss and ultrastructure alterations of oocyte. this study was performed to determine the effect of daily supplementation of vitamin e on oocytes apoptosis in nicotine-treated mice. materials and methods in this experimental study, 24 nmari adult female mice were randomly allocated into four experimental groups. for...

Background: Nicotine is a major toxic component of cigarette smoke and it is a major risk factor in the development of functional disorder of several organ systems. Resveratrol (trans-3,5,4'-trihydroxystilbene; RES) is a naturally occurring polyphenol synthesized by a variety of plant species in response to injury, UV irradiation and fungal attack. It is present in grapes, berries, peanuts...

Increased activity of mesolimbic dopaminergic system within ventral tegmental area (VTA) due to nicotine results in psychologic dependence. It has been argued that function of dopamine receptors could by affected by ascorbic acid (AA). Furthermore, AA can decrease the withdrawal syndrome signs in addicted animals and may postpone the development of nicotine dependence. In the present study, the...