Fig. 1. Effect of rifamycins on RNA polymerase reactions of E. coli and Ehrlich carcinoma cells. The reaction mixture for the assay of E. coli RNA polymerase contained (0.3 ml) Tris-HCl, pH 8.0, 15 //moles; /?-mercaptoethanol, 3.6 //moles; MgCl2, 1.2 //moles; MnCl2, 0.3 //moles; ATP, GTP and UTP, 0.1 //mole each; 3H-CTP, 0.05 //moles (3,000 cpm/m/zmole); calf thymus DNA, 30 jug, enzyme, 20jug. ...

BACKGROUND Moles, or melanocytic nevi, are both markers of an increased risk of cutaneous melanoma and direct precursor lesions. Recent strategies to reduce the burden of advanced disease have focused on early detection and ongoing surveillance of moles for malignant degeneration. Inherent in this approach is the notion that moles exhibit a certain risk of transformation into melanoma; however,...

In diesem Beitrag beschreiben wir die iterative Entwicklung der Applikation Moles (Mobile Learning Exploration System). Mit Moles werden Entdeckungstouren, fachliche Exkursionen aber auch mobile Lernspiele für Kinder und Jugendliche im schulischen Kontext erstellt, durchgeführt und nachbearbeitet. Die laufende Weiterentwicklung des Systems beruht auf kontinuierlichen Evaluationen im Feld sowie ...

STUDY QUESTION How does tetraploidy develop in hydatidiform moles (HMs), and what is the frequency of the different origins? SUMMARY ANSWER Most molar pregnancies with tetraploid cells appear to be produced by somatic endoreduplications, while a minority originate from a tetraploid zygote. The frequency of zygotic tetraploidy was estimated to be 0.7%. WHAT IS KNOWN ALREADY The parental orig...

Most dermatologists can perform cosmetic mole removals (this is not something to try at home with your trusty disposable razor). To take off an elevated mole, a dermatologist numbs the area with local anesthetic and then shaves off the raised section of the mole with a sterile scalpel. The healing process usually leaves a flat scar that's somewhat lighter than the rest of your skin. Sometimes t...

Moles are considered pests in Britain, but this issue has been little studied. Lower welfare standards have been tolerated for moles than for most other managed wild mammal species, as use of both the controversial poison, strychnine, and unregulated traps have been permitted. Strychnine was withdrawn in 2006 and there were fears that mole populations would increase as a result. In 2007, we con...

Atypical moles are benign pigmented lesions. Although they are benign, they exhibit some of the clinical and histologic features of malignant melanoma. They are more common in fair-skinned individuals and in those with high sun exposure. Atypical moles are characterized by size of 6 mm or more at the greatest dimension, color variegation, border irregularity, and pebbled texture. They are assoc...

Sixteen hairy-tailed moles, Parascalops breweri, collected from the northeastern U.S.A. were examined for coccidian oocysts; all were infected with multiple species of coccidia and 3 genera were represented. Two cyclosporans, 2 eimerians, and 2 isosporans are described as new species. Sporulated oocysts of Cyclospora ashtabulensis n. sp. are subspheroid to ellipsoid, 18 X 14 (14-23 X 11-19) mic...

Sea water samples were collected from 32 stations in the southern part of the Persian Gulf and the Gulf of Oman during winter of 1987. Surface water of the Persian Gulf exhibited wide range and higher values of salinity (37.15-43.95, mean 40.02%) compared with lower values and narrow range (36.58-36.95, mean 36.74%) in the Gulf of Oman. Surface salinity did not reflect any significant relations...