نتایج جستجو برای: mismatch repair genes
تعداد نتایج: 571705 فیلتر نتایج به سال:
Excessive recombination between repeated, interspersed, and diverged DNA sequences is a potential source of genomic instability. We have investigated the possibility that a mechanism exists to suppress genetic exchange between these quasi-homologous (homeologous) sequences. We examined the role of the general mismatch repair system of Escherichia coli because previous work has shown that the mi...
Somatic mutations in DNA mismatch repair genes have been observed in sporadic tumors as well as ceHlines and xenografts derived from such tumors implicating genetic defects of mismatch repair genes in the devel opment of such tumors. However, the proportion of sporadic tumors in which mismatch repair genes have been inactivated has not been deter mined accurately. We have analyzed 66 sporadic c...
Somatic mutations in DNA mismatch repair genes have been observed in sporadic tumors as well as cell lines and xenografts derived from such tumors implicating genetic defects of mismatch repair genes in the development of such tumors. However, the proportion of sporadic tumors in which mismatch repair genes have been inactivated has not been determined accurately. We have analyzed 66 sporadic c...
UNLABELLED Correction of misincorporated nucleotides during DNA replication (mismatch repair) distinguishes histologically similar cancers with distinct biological and clinical behavior. We investigated expression of two mismatch repair genes in testis cancer to determine the expression pattern in histologically distinct subtypes, correlate expression with genetic instability and correlate expr...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید