نتایج جستجو برای: methylpyrimidine

تعداد نتایج: 151  

Journal: :Cancer research 1982
S F Zakrzewski Z Pavelic W R Greco G Bullard P J Creaven E Mihich

The toxicology of a potentially useful antitumor agent, 2,4-diamino-5-adamantyl-6-methylpyrimidine (DAMP), and its ethanesulfonate salt has been studied in beagle dogs after 1 to 20 doses. Two types of toxicity could be discerned: the acute central nervous system toxicity manifested by vomiting, convulsions, and minor hypothermia; and the antiproliferative toxicity, similar to that of other fol...

Journal: :The Journal of vitaminology 1957
Y NISHIZAWA T KODAMA T KOOKA

Abderhalden (1) injected the pyrimidine and thiazole moieties of thiamine in mice and rats with the object of investigating the biosynthesis of thiamine and observed the induction of running fits. Its cause was further proved to be the pyrimidine moiety, i.e., 2-methyl-4-amino-5-hydroxymethylpyrimidine (OMP). Makino and Sasaki (2) reported the induction of running fits after in jecting this com...

Journal: :analytical and bioanalytical chemistry research 2014
m.reza hormozi-nezhad sena ghayyem

we report herein the development of a highly sensitive colorimetric method for the detection of 4-hydroxy-2-mercapto-6-methylpyrimidine (mtu) which acts as an anti-thyroid drug utilizing citrate capped gold nanoparticles (au-nps). this thiol-containing molecule exhibits intriguing affinity with au-nps. the reactivity involves the displacement of the citrate shell by the thiolate shell followed ...

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