نتایج جستجو برای: metabolomics
تعداد نتایج: 12395 فیلتر نتایج به سال:
We elucidate major pathways of hepatocarcinogenesis and accurate diagnostic metabolomic biomarkers of hepatocellular carcinoma (HCC) identified by contemporary HCC metabolomics studies, and delineate a model HCC metabolomics study design. A literature search was carried out on Pubmed for HCC metabolomics articles published in English. All relevant articles were accessed in full text. Major sear...
Metabolomics studies the occurrence and change of concentrations of small molecular weight chemical compounds (metabolites) in organisms, organs, tissues, cells and ultimately cell compartments in the context of environmental changes, disease or other boundary conditions. It does this by means of spectroscopic and chromatographic techniques and by observing at once not only a few but all compou...
Bioassays are used for the assessment of environmental pollution and risk assessment of environmental stresses. In bioassay systems, harmless is estimated by monitoring biological responses to environmental stress. An extensive literature exists on bioassay systems that include tests by Ames, Microtox, Umu, and others. These traditional bioassays did contribute to prevent adverse effect of chem...
Metabolomics is a rapidly expanding field of systems biology that is gaining significant attention in many areas of biomedical research. Also known as metabonomics, it comprises the analysis of all small molecules or metabolites that are present within an organism or a specific compartment of the body. Metabolite detection and quantification provide a valuable addition to genomics and proteomic...
Chemical biology Beginner 0.5 hour Join Reza Salek on an introductory tour of metabolomics. This webinar will help you understand what metabolomics is and how it can be used to inform biological research. It will also introduce the basics of the analytical technologies and data analysis methods commonly used in metabolomics. This webinar was recorded on 8 February 2017. It is best viewed in ful...
Metabolomics is based on the simultaneous analysis of multiple low-molecular-weight metabolites from a given sample. The goals of metabolomics are to catalog and quantify the myriad small molecules found in biological fluids under different conditions. The metabolomics represents the collection of all metabolites in a biological organism, and metabolic profiling can give an instantaneous 'snaps...
Article history: Received on: 22/09/2013 Revised on: 6/10/2013 Accepted on: 20/10/2013 Available Online: 30/10/2013 Metabolomics plays significant roles in plant biology including growth, development and stress resistance. Plant produces diverse array of metabolites (approximately 200,000 to 1,000,000); hence metabolomic study is of great importance in plant biology. Due to presence of diverse ...
Metabolomics use in toxicology is rapidly increasing, particularly owing to advances in mass spectroscopy, which is widely used in the life sciences for phenotyping disease states. Toxicology has the advantage of having the disease agent, the toxicant, available for experimental induction of metabolomics changes monitored over time and dose. This review summarizes the different technologies emp...
Metabolomics is the methodology that identifies and measures global pools of small molecules (of less than about 1,000 Da) of a biological sample, which are collectively called the metabolome. Metabolomics can therefore reveal the metabolic outcome of a genetic or environmental perturbation of a metabolic regulatory network, and thus provide insights into the structure and regulation of that ne...
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