INTRODUCTION Cancer diagnosis is an extremely stressful experience that has a profound impact on a patient's life. Cancer related perceived stress and complications may lead to the experience of positive psychological changes and post-traumatic growth (PTG). Since there is lack of qualitative research assessing the experience of PTG in Iranian women with breast cancer, this study aims to invest...

BACKGROUND Polycystic ovary syndrome (PCOS) is associated with metabolic abnormalities which are also parts of metabolic syndrome (MetS). It is debated whether all women with PCOS should be screened for MetS and Insulin resistance (IR), since they may vary in terms of PCOS phenotype, ethnicity and age. This large scale study aimed to determine the prevalence of MetS among Iranian women diagnose...

The association of obesity and other metabolic conditions with osteoarthritis is under debate; however, a strong link between metabolic disturbances is suggested to contribute to increased incidences and progression of osteoarthritis. We examined the association of metabolic syndrome and its components with the incidence of knee osteoarthritis in Iranian population. A community-based study was ...

BACKGROUND Failed visualization of the fetal nasal bone (NB) by ultrasound at 11 - 14 weeks of gestation is strongly associated with chromosomal abnormalities. Meanwhile, the incidence of the absent fetal NB in normal fetuses in the first trimester in mothers of different ethnic origins differs significantly. It is, therefore, important to assess ethnic variations in the first-trimester visuali...

The prevalence of hypertension, diabetes, dyslipidemia, and metabolic syndrome are increasing globally. The present study was conducted in an attempt to define optimal cutoff values for several anthropometric variables in an Iranian population, as these may vary with ethnicity. Iranian subjects (2483 men and 2445 women), aged 15-65 years, were recruited using a cluster-stratified sampling metho...

BACKGROUND To assess maternal confidence in her ability to cope with labor, a measure of childbirth self efficacy is necessary. OBJECTIVES This paper aims to assess the cultural adaptation and psychometric testing of the short form of childbirth self-efficacy Inventory among Iranian pregnant women. PATIENTS AND METHODS In this descriptive-methodological study, we investigated 383 Iranian pr...

BACKGROUND Limited studies have examined the relationship between quality of life and lifestyle behaviors. The purpose of this study is to examine the perceptions of quality of life among young Iranian women and its association with lifestyle behaviors. METHODS This cross-sectional study was conducted among 391 young women selected through a cluster convenience sampling strategy in Shiraz, Ir...

BACKGROUND Cytochrome P450 2C19 (CYP2C19) is important in metabolism of wide range of drugs. CYP2C19*17 is a novel variant allele which increases gene transcription and therefore results in ultra-rapid metabolizer phenotype (URM). Distribution of this variant allele has not been well studied worldwide. The aim of present study was to investigate allele and genotype frequencies of CYP2C19*17 in ...

leptin, a circulating 16-kd polypeptide consisting of 167 amino acids, appears to be involved in the body weight homeostasis. moreover leptin plays an important role for the reproductive system, early embryogenesis, and fat metabolism during pregnancy and puberty. significant correlations have been found between leptin and sexual hormones, which is a cytokine and has hormonal properties. the ai...