Background: In spite of different methods of treatment, there is not a simple, safe and complete curative treatment for cutaneous Leishmaniasis (CL), yet. Objective: To compare the efficacy of intralesional Glucantime injection alone, with the combined triple therapy of cryotherapy, paramomycin ointment and intralesional Glucantime in the treatment of CL. Materials and methods: 157 patien...

background: bone marrow mesenchymal stem cells (bmscs) are the key to regenerative wound healing. mscs have spatial memory and respond to local environment. the goal of this study was to evaluate the use of systemic and intralesional transplantation of bmscs for regeneration of oral mucosa in an in vivo dog model. materials and methods: transplantation of undifferentiated green fluorescent prot...

salivary mucocele is a common lesion derived from minor salivary glands with various surgical or non-surgical treatment modalities. to evaluate the effect of a highly potent corticosteroid (dexamethasone) in the management of salivary mucocele, we performed intralesional injection of dexamethasone in nine patients with labial mucocele. complete healing of lesions observed in seven of nine patie...

INTRODUCTION Few studies have evaluated the efficacy of intralesional bleomycin injection combined with electroporation for the treatment of cutaneous tumors. However, the phenomenon that electroporation can enhance the cytotoxicity of bleomycin in vivo by 300-700 fold has been intensely investigated. CASE PRESENTATION Keratoacanthoma in an 86-year-old patient was treated with intralesional b...

and efficacy of treatment in patients with LC in the course of BCLL are controversial. Many authors describe poor prognosis, when LC shows blastic transformation, known as Richter’s syndrome, and when it appears after the diagnosis of B-CLL. The potential benefit of treating only skin lesions has not been documented; however, these patients rarely stay without treatment. Numerous therapeutic mo...

The pretibial myxedema is a manifestation of Graves' disease characterized by accumulation of glycosaminoglycans in the reticular dermis. The dermopathy is self-limiting but in some cases may cause cosmetic and functional damage. Conventional treatment is use of topical steroids under occlusive dressing, however the intralesional application has shown good results. We present a case of pretibia...

The proper treatment of cartilaginous tumors is dependent on the clinicopathologic and radiologic findings. Enchondroma is a benign tumor that is usually asymptomatic and thus should be treated nonoperatively. Symptomatic enchondromas are often treated by intralesional excision. Intramedullary low-grade chondrosarcoma is a malignant tumor that is usually painful. The treatment of low-grade chon...