نتایج جستجو برای: interictal epileptiform discharge

تعداد نتایج: 104913  

2009
Catherine A. Schevon A. J. Trevelyan C. E. Schroeder R. R. Goodman G. McKhann R. G. Emerson

Interictal high frequency oscillations (HFOs), in particular those with frequency components in excess of 200 Hz, have been proposed as important biomarkers of epileptic cortex as well as the genesis of seizures. We investigated the spatial extent, classification and distribution of HFOs using a dense 4 x 4 mm(2) two dimensional microelectrode array implanted in the neocortex of four patients u...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2003
Volodymyr I Dzhala Kevin J Staley

The transition from brief bursts of synchronous population activity characteristic of interictal epileptiform discharges (IEDs) to more prolonged epochs of population activity characteristic of seizures (ictal-like activity) was recorded in juvenile rat hippocampal-entorhinal cortex slices and hippocampal slices using multiple-site extracellular electrodes. Epileptiform activity was elicited by...

2013
ZUCAI XU JUN ZHANG XIANZE LEI ZHONGXIANG XU YAN PENG BENHAI YAO PING XU

The aim of the present study was to investigate the effects of valproate sodium (VPAS) on the phosphorylation extracellular signal-regulated kinase 1/2 (ERK1/2) following hippocampal neuronal epileptiform discharge in rat neurons. The study used neurons from female and male neonate Sprague-Dawley (SD) rats (at least 24 h old), which were rapidly decapitated. Following the successful development...

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