Oral polio vaccine (OPV) and Inactivated Polio Vaccine (IPV) have distinct advantages and limitations. IPV does not provide mucosal immunity and introduction of IPV to mitigate consequences of circulating vaccine-derived polio virus from OPV has very limited effect on transmission and OPV campaigns are essential for interrupting wild polio virus transmission, even in developed countries with a ...

WHO has confi rmed an outbreak of at least ten cases of polio in Syria, where vaccination coverage has dramatically decreased during the civil war. Furthermore, wild-type poliovirus 1 (WPV1) has been isolated from sewage and faeces from asymptomatic carriers in Israel since February, 2013. Tourists and travellers could bring the infection to other countries. Precautions during the Hajj in Saudi...

The Epidemiology of poliomgelitis has been investigated in our country Pasteur Institute; the incidence of Poliomgelitis, after the age of 4 years i's rare, in Iran.  Passive antibody of maternal origin do not interfere with production of active antibody after immunization.  Inactivated Polio Vaccine (salk) has been effective in reducing the incidence of poliomge­litis by approximately 90 per ...

Global polio eradication is closer than ever. Replacement of the live attenuated oral poliovirus vaccine (OPV) by inactivated poliovirus vaccine (IPV) is recommended to achieve complete eradication. Limited global production capacity and relatively high IPV costs compared to OPV spur the need for improved polio vaccines. The target product profile of these vaccines includes not only dose sparin...

Given the actual risk of poliomyelitis outbreaks in region due to poliovirus derived from Sabin vaccine or importation wild poliovirus, Latin American Society Pediatric Infectious Diseases commissioned an ad hoc group experts institution's Vaccines and Biologicals Committee, draft official position paper on urgent need increase immunization levels against disease incorporate inactivated polio e...

Enterococcus mundtii ST4V, isolated from soya beans, produces a 3950Da antibacterial peptide active against Gram-positive and Gram-negative bacteria, including Enterococcus faecalis, Streptococcus spp., Pseudomonas aeruginosa, Klebsiella pneumoniae, Streptococcus pneumoniae and Staphylococcus aureus. The peptide also inactivated the herpes simplex viruses HSV-1 (strain F) and HSV-2 (strain G), ...

Australia, along with 36 other countries in the Western Pacific Region, was declared free of poliomyelitis by the World Health Organization in October 2000. Yet, the persistence of wild poliovirus in the 4 remaining polio-endemic countries-Afghanistan, India, Nigeria, and Pakistan-poses a risk for its importation into all countries declared polio free. We describe the public health response and...

In Canada, the fifth dose of the routine childhood immunization schedule against diphtheria, tetanus, pertussis and polio is given at 4-6 years of age. Up to 30% of children may have significant local reactions (redness, swelling) and this may be related to pertussis and diphtheria antigen content. We sought to determine if a combination product with lower content of pertussis and diphtheria to...