نتایج جستجو برای: immune mediated disease
تعداد نتایج: 2013882 فیلتر نتایج به سال:
background: immune thrombocytopenic purpura (itp) is an autoimmune disease that can cause bleeding disorders in patients, and presents in acute and chronic forms. the acute form is frequently seen in children, but the chronic form mainly inflicts adults. there are differences and similarities in clinical and laboratory findings of the disease between children and adults. we study these differen...
Abstract The oral cavity is a unique stricture; it combines mucosal and bone tissue microenvironments with their respective immunological responses. In fact, inflammation leads to destruction in the prevalent human disease, periodontitis. periodontitis, immune cells, particular Th17 neutrophil mediated responses have been linked pathogenesis, however not yet understood how stromal microenvironm...
the cd30 antigen seems to play a costimulatory role in maintaining the physiological balance between t-helper (th)1/th2 immune responses. in this study, plasma and in vitro soluble cd30 (scd30) secretion was investigated in patients with coronary artery disease (cad) as a plausible marker of dysregulated immune response. twenty one patients with angiographically confirmed cad and 31 healthy con...
Fibrosing colonopathy, a recently described complication of patients with cystic fibrosis, manifests clinically approximately 7-12 months after starting high dose pancreatic enzyme treatment. Although the pathogenesis of fibrosing colonopathy is unknown, it is highly correlated with pancreatic enzyme dose. In this study, immune mediated factors which may be associated with fibrosing colonopathy...
Narcolepsy is a neurological disorder characterized by excessive daytime sleepiness, cataplexy, hypnagonic hallucinations, sleep paralysis, and disturbed nocturnal sleep patterns. This disease is secondary to the specific loss of hypothalamic hypocretin (orexin)-producing neurons in the lateral hypothalamus. An autoimmune basis for the disease has long been suspected based on its strong associa...
The link between oncology and immunology has a long history and its development is forced by the necessity to develop innovative and highly efficient modalities for immunological destruction of malignant cells. The limited efficacy of surgery, chemotherapy and radiation also exemplify these issues, as these treatments do not eliminate all cancerous cells, do not address the immunosuppressive na...
Background: Multiple Sclerosis (MS), the most common demyelinating disease of the CNS, is immunologically mediated in genetically susceptible individuals. Receptors for the Fc fragment of IgG (FcγR) might induce inflammatory responses through linking the humoral and cellular immune responses by targeting immune complexes to effector cells. Polymorphisms in some FcγR genes are associated with va...
To analyze in several immune-mediated inflammatory diseases (IMIDs) the influence of demographic and clinical-related variables on the prevalence of cardiovascular disease (CVD), and compare their standardized prevalences.Cross-sectional study, including consecutive patients diagnosed with rheumatoid arthritis, psoriatic arthritis, psoriasis, systemic lupus erythematosus, Crohn disease, or ulce...
Cell-mediated immunity has been investigated using the leucocyte migration test in 32 patients with chronic active hepatitis or primary biliary cirrhosis. Twenty-six (75%) showed reactivity to liver extract. At least two antigens are involved. Cell-mediated reactivity was confirmed in some cases using lymphocyte ;blast' transformation. There was no correlation with the presence of auto-antibodi...
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