10. Parr GVS, Kirklin JW, Pacifico AD, Blackstone EH, Lauridsen P: Cardiac performance in infants after repair of total anomalous pulmonary venous connection. Ann Thorac Surg 17: 561, 1974 11. Barratt-Boyes BG: Primary definitive intra-cardiac operations in infants: Total anomalous pulmonary venous connection. In Advances in Cardiovascular Surgery, edited by Kirklin JW. New York, Grune and Stra...

Previous studies have demonstrated the anti-hypertensive effects of Hibiscus sabdariffa L. (HS) in both humans and experimental animals. To explore the mechanisms of the anti-hypertensive effect of the HS, we examined the effects of a crude methanolic extract of the calyces of HS (HSE) on vascular reactivity in isolated aortas from spontaneously hypertensive rats. HSE relaxed, concentration-dep...

Introduction :Vitamin D deficiency is associated with hypertension; however, there is no study on the relationship between vitamin D deficiency and hypertensive crises. This study aimed to determine the relationship between serum vitamin D levels and hypertensive crises. Materials and Methods: This descriptive-analytical, cross-sectional study was conducted on 120 individuals in Shafa Hospital ...

1. Atenolol (ICI 66.082, Tenormin) is a new beta-adrenoreceptor-blocking agent, devoid of intrinsic sympathomimetic and membrane-stabilizing properties. It does not cross the blood-brain barrier. 2. Atenolol given to hypertensive patients in initial open trials reduced arterial blood pressure significantly. 3. A double-blind comparison between atenolol and placebo in forty-five patients with es...

BACKGROUND/AIM The effects of AT2 receptor agonist novokinin on blood pressure, eNOS, NADPH oxidase, protein arginine methyltransferases (PRMTs), and Rho kinase in hypertension were investigated. Furthermore, in isolated thoracic aorta rings, contractile and dilator responses were studied. MATERIALS AND METHODS To develop hypertension, L-NAME was administered intraperitoneally and salt was gi...

Hypertensive diabetes individuals are at higher risk for cardiovascular events and progression to end stage renal disease. Several well conducted clinical trials indicate that aggressive treatment of hypertension in individual with diabetes reduces these complications. Combinations of two or more antihypertensive drugs are frequently required to reach the target blood pressure and to improve th...

The blood pressure of rabbits with chronic one-kidney hypertension can be lowered to normal by immunization with hog kidney cortex preparations that do not contain renin, thus providing evidence for a new factor essential for the maintenance of an elevated blood pressure. A search for the new factor has led to the discovery of a hypertensive substance which we have named renopressin. Subcutaneo...

This study examined whether hypertension attenuated cell-to-cell communication in skeletal muscle resistance arteries. Briefly, arteries feeding the retractor muscle of normotensive and hypertensive hamsters were cannulated, pressurized, and superfused with a physiological saline solution. Cell-to-cell communication was functionally assessed by application of vasoactive stimuli (via micropipett...

INTRODUCTION Hypertension (HTN), being a major risk factor for cardiovascular diseases (CVDs), is an important issue of medical and public health. High blood pressure (BP) is ranked as the third most important risk factor for attributable burden of disease in south Asia (2010). Hypertension (HTN) exerts a substantial public health burden on cardiovascular health status and healthcare systems in...

Acute ballistocardiographic responses to five hypotensive drugs have been evaluated in 15 patients with essential hypertension in conjunction with depressor effects. In the majority of experiments qualitative and quantitative ballistocardiographic improvement paralleled the pressure reductions. On occasion the reverse was true. Inferences were drawn from these reactions based on the pharmacodyn...