نتایج جستجو برای: hyperlipoproteinemia
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Type III is a remnant hyperlipoproteinemia identified by the presence of beta-VLDL (remnant lipoprotein) as well as a genetic variant of apo E (apo E2/2). The RLP isolated from the serum of Type III patients by a new method we have developed, the RLPcholesterol assay, was identified as chylomicron and VLDL remnant. In addition, the RLP-C levels of the Type III patients were significantly higher...
Using apoE phenotyping by immunoblotting and apoE genotyping we identified four heterozygous carriers of a rare apolipoprotein (apo) E2 variant, apoE2 (Arg 136 → Cys). ApoE2 (Arg 136 → Cys) was not distinct from apoE2 (Arg 158 → Cys) by phenotyping, but produced a unique pattern of bands on Cfo I restriction typing of a 244 bp apoE gene fragment. Two of the four apoE2 (Arg 136 → Cys)/3 heterozy...
We describe a new phenotype of hyperlipoproteinemia in two members of a family with a high degree of consanguinity. Both have a history of uncontrolled diabetes mellitus without ketoacidosis, and a family history of coronary artery disease at a relatively early age. A high degree of insulin resistance was found. The abnormal lipoprotein(s) has alpha-lipoprotein mobility on cellulose acetate ele...
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