OBJECTIVES To assess the feasibility of detecting new cases of heterozygous familial hypercholesterolaemia by using a nurse led genetic register. DESIGN Case finding among relatives of patients with familial hypercholesterolaemia. SETTING Two lipid clinics in central and south Manchester. SUBJECTS 259 (137 men and 122 women) probands and 285 first degree relatives. RESULTS Of the 200 fi...

BACKGROUND A better understanding of patients' and physicians' perceptions and experience of hypercholesterolaemia will help to improve cardiovascular disease prevention and aid the development of appropriate educational strategies. AIM To identify perceptions, experience, educational needs, and barriers to learning in hypercholesterolaemic patients at high risk of cardiovascular disease. D...

(project number 95/29/04). The opinions expressed therein are those of the authors and not necessarily those of the NHS Executive. DM was supported in the preparation of this paper by an unconditional grant from Merck Sharpe and Dohme. SEH and HAWN acknowledge grants RG2000025 and RG93008 from the British Heart Foundation. of underdiagnosis of familial hypercholesterolaemia in routine practice:...

There is an increase prevalence of chronic non-communicable diseases in the Caribbean as the region undergoes an epidemiologic transition from infectious to chronic non-communicable diseases. Numerous studies have identified hypertension, obesity, diabetes mellitus and hyperlipidaemia as risk factors for the development of coronary atherosclerosis. The Caribbean Cardiac Society recognizes that ...

BACKGROUND Studies have been conducted on supplementing the daily diet with plant sterol ester-enriched milk derivatives in order to reduce LDL-cholesterol levels and, consequently, cardiovascular risk. However, clinical practice guidelines on hypercholesterolaemia state that there is not sufficient evidence to recommend their use in subjects with hypercholesterolaemia. The main objective of th...

It is generally accepted that a vegetarian diet and especially a vegan diet is associated with a low serum cholesterol.",2'3 When vegans are surveyed they have a significantly lower intake of total energy and especially energy from fat4 and their mean serum total cholesterol is also lower than expected values for the normal population.5 We present a patient who was a strict vegan but had a high...