Lipitor tablets for oral administration contain 10, 20, 40 or 80 mg atorvastatin and the following inactive ingredients: calcium carbonate, USP; candelilla wax, FCC; croscarmellose sodium, NF; hydroxypropyl cellulose, NF; lactose monohydrate, NF; magnesium stearate, NF; microcrystalline cellulose, NF; Opadry White YS-1-7040 (hypromellose, polyethylene glycol, talc, titanium dioxide); polysorbat...

The main objective of this study was to develop mebeverine hydrochloride colon targeted drug delivery system using compression coating technique for effective treatment of irritable bowel syndrome. This work was mainly focused on the formulation & in-vitro evaluation of compression coated tablets of mebeverine hydrochloride with different pH dependent polymers like Eudragit L100-55, hydroxyprop...

In this study, cationic cellulose (CC) was prepared by etherifying commercial with (3-chloro-2 hydroxypropyl) trimethylammonium chloride (CHPTAC) in an alkaline medium. The CC characterized using Fourier transform infrared spectrometry (FTIR), scanning electron microscopy (SEM), differential calorimetry (DSC), and nuclear magnetic resonance (NMR). characterization results affirmed the successfu...

The present work reports on the use of a hybrid blend biopolymers as matrix for lipase immobilization. (Hydroxypropyl)methyl cellulose (HPMC) and Chitosan (CS) were combined in order to formulate film which Mucor miehei was immobilized. biocatalyst studied upon model reaction propyl laurate synthesis. system examined terms its capability provide an appropriate environment where will maintain ac...

hypertension crisis is one of the main health problems and its effective treatment is of high importance. for this purpose, fast-disintegrating and sustained release formulations of captopril, as a drug of choice, were prepared using conventional mucoadhesive polymers hydroxypropyl methylcellulose (hpmc), sodium carboxymethyl cellulose (na-cmc), hydroxypropyl cellulose (hpc), carbopol 934 (cp93...

the purpose of this work was to study the effect of various permeation enhancers on the permeation of salbutamol sulphate (ss) buccal patches through buccal mucosa in order to improve the bioavailability by avoiding the first pass metabolism in the liver and possibly in the gut wall and also achieve a better therapeutic effect. the influence of various permeation enhancers, such as dimethyl sul...

Glipizide is mainly absorbed in the proximal areas of the gastrointestinal tract. The purpose of this study was formulation and evaluation of mucoadhesive films to prolong the stay of drug in its absorption area. Glipizide was formulated in a mucoadhesive film that could be retained in the stomach for prolonged intervals. Polymeric films were designed with various compositions of hydroxypropyl ...

The development of liquid crystal materials via nanotechnology has become an interesting subject research in optical material chemistry. One the significant nanomaterials is cellulose-based nanoparticles. In this review article, we highlighted classification (LCs), and types cellulose-NPs their characterization as LCs materials. Finally, present our promising data on synergistic effect behavior...