نتایج جستجو برای: hips cells

تعداد نتایج: 1387627  

Journal: :Journal of molecular cell biology 2014
Hussain Md Shahjalal Nobuaki Shiraki Daisuke Sakano Kazuhide Kikawa Soichiro Ogaki Hideo Baba Kazuhiko Kume Shoen Kume

Human induced pluripotent stem (hiPS) cells are considered a potential source for the generation of insulin-producing pancreatic β-cells because of their differentiation capacity. In this study, we have developed a five-step xeno-free culture system to efficiently differentiate hiPS cells into insulin-producing cells in vitro. We found that a high NOGGIN concentration is crucial for specificall...

Journal: :medical journal of islamic republic of iran 0
f abdinejad assistant professor of orthopedic surgery, department of orthopedicsurgery, shiraz university of medical sciences, shiraz , islamic republic of iran. j takapouy residents of orthopedic surgery, shiraz university of medical sciences, shiraz, islamic republic of iran. n eskandari residents of orthopedic surgery, shiraz university of medical sciences, shiraz, islamic republic of iran.

during an eight month prospective study, 8240 newborns were examined for detection of congenital dislocation of the hip from oct. 23, 1991 to june 22, 1992. on first examination we found 1302 neonates (158/1000 live births) to have abnormal hips 1063 (81.6%) were prone to subluxation (subluxatable), 218 (16.81 %) prone to dislocation (dislocatable), 17 (1.3%) were dislocated and 4 (0.3%) were t...

ژورنال: :فصلنامه علوم پزشکی دانشگاه آزاد اسلامی واحد پزشکی تهران 0
الهام حویزی elham hoveizi department of biology, faculty of sciences, shahid chamran university of ahvaz, ahvaz, iranگروه زیست شناسی، دانشکده علوم، دانشگاه شهید چمران اهواز طیبه محمدی tayebeh mohammadi department of biology, faculty of sciences, shahid chamran university of ahvaz, ahvaz, iranگروه زیست شناسی، دانشکده علوم، دانشگاه شهید چمران اهواز

سابقه و هدف: سلول­های پرتوان القا شده انسانی (hips) به عنوان یکی از منابع جدید، به منظور تولید سلول­های تمایز یافته برای سلول درمانی مورد توجه هستند. سلول­های hips می­توانند در زمینه تحقیقات چندگانه و ابزارهای بالینی برای درک مدل­های حیوانی، تکوین وغربالگری داروهای کاندید و سلول درمانی در حمایت از طب ترمیمی مورد استفاده قرار گیرند. در اینجا ما توان تمایزی  سلول­های hips به سلول های استئوبلاست و...

2015
Shuhei Konagaya Takeshi Ando Toshiaki Yamauchi Hirofumi Suemori Hiroo Iwata

Pluripotent stem cells, such as embryonic stem cells and induced pluripotent stem (iPS) cells, are regarded as new sources for cell replacement therapy. These cells can unlimitedly expand under undifferentiated conditions and be differentiated into multiple cell types. Automated culture systems enable the large-scale production of cells. In addition to reducing the time and effort of researcher...

2010
Kenji Yasuda Tomoyuki Kaneko Fumimasa Nomura

Cells are minimum units reflecting epigenetic information, which is considered to map the history of a parallelprocessing recurrent network of biochemical reactions, their behaviors cannot be explained by considering only conventional DNA information-processing events. We have developed methods and systems of analyzing epigenetic information in cells, as well as that of genetic information, to ...

2011
Naoki Yahata Masashi Asai Shiho Kitaoka Kazutoshi Takahashi Isao Asaka Hiroyuki Hioki Takeshi Kaneko Kei Maruyama Takaomi C. Saido Tatsutoshi Nakahata Takashi Asada Shinya Yamanaka Nobuhisa Iwata Haruhisa Inoue

BACKGROUND Alzheimer's disease (AD) is a neurodegenerative disorder that causes progressive memory and cognitive decline during middle to late adult life. The AD brain is characterized by deposition of amyloid β peptide (Aβ), which is produced from amyloid precursor protein by β- and γ-secretase (presenilin complex)-mediated sequential cleavage. Induced pluripotent stem (iPS) cells potentially ...

Journal: :The American Journal of Sports Medicine 2016

2016
Vasco Meneghini Giacomo Frati Davide Sala Silvia De Cicco Marco Luciani Chiara Cavazzin Marianna Paulis Wieslawa Mentzen Francesco Morena Serena Giannelli Francesca Sanvito Anna Villa Alessandro Bulfone Vania Broccoli Sabata Martino Angela Gritti

Allogeneic fetal-derived human neural stem cells (hfNSCs) that are under clinical evaluation for several neurodegenerative diseases display a favorable safety profile, but require immunosuppression upon transplantation in patients. Neural progenitors derived from patient-specific induced pluripotent stem cells (iPSCs) may be relevant for autologous ex vivo gene-therapy applications to treat gen...

Journal: :Proceedings of the Royal Society of Medicine 1939

Journal: :Bone 2011
Valérie Gangji Viviane De Maertelaer Jean-Philippe Hauzeur

OBJECTIVE To determine the efficacy of bone marrow cell implantation into the necrotic lesion of the femoral head on clinical symptoms and the progression of osteonecrosis of the femoral head in comparison with core decompression. METHODS We studied nineteen patients and twenty four hips with early stage osteonecrosis of the femoral head. The hips were allocated to either core decompression o...

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