نتایج جستجو برای: hips cells
تعداد نتایج: 1387627 فیلتر نتایج به سال:
Human induced pluripotent stem (hiPS) cells are considered a potential source for the generation of insulin-producing pancreatic β-cells because of their differentiation capacity. In this study, we have developed a five-step xeno-free culture system to efficiently differentiate hiPS cells into insulin-producing cells in vitro. We found that a high NOGGIN concentration is crucial for specificall...
during an eight month prospective study, 8240 newborns were examined for detection of congenital dislocation of the hip from oct. 23, 1991 to june 22, 1992. on first examination we found 1302 neonates (158/1000 live births) to have abnormal hips 1063 (81.6%) were prone to subluxation (subluxatable), 218 (16.81 %) prone to dislocation (dislocatable), 17 (1.3%) were dislocated and 4 (0.3%) were t...
سابقه و هدف: سلولهای پرتوان القا شده انسانی (hips) به عنوان یکی از منابع جدید، به منظور تولید سلولهای تمایز یافته برای سلول درمانی مورد توجه هستند. سلولهای hips میتوانند در زمینه تحقیقات چندگانه و ابزارهای بالینی برای درک مدلهای حیوانی، تکوین وغربالگری داروهای کاندید و سلول درمانی در حمایت از طب ترمیمی مورد استفاده قرار گیرند. در اینجا ما توان تمایزی سلولهای hips به سلول های استئوبلاست و...
Pluripotent stem cells, such as embryonic stem cells and induced pluripotent stem (iPS) cells, are regarded as new sources for cell replacement therapy. These cells can unlimitedly expand under undifferentiated conditions and be differentiated into multiple cell types. Automated culture systems enable the large-scale production of cells. In addition to reducing the time and effort of researcher...
Cells are minimum units reflecting epigenetic information, which is considered to map the history of a parallelprocessing recurrent network of biochemical reactions, their behaviors cannot be explained by considering only conventional DNA information-processing events. We have developed methods and systems of analyzing epigenetic information in cells, as well as that of genetic information, to ...
BACKGROUND Alzheimer's disease (AD) is a neurodegenerative disorder that causes progressive memory and cognitive decline during middle to late adult life. The AD brain is characterized by deposition of amyloid β peptide (Aβ), which is produced from amyloid precursor protein by β- and γ-secretase (presenilin complex)-mediated sequential cleavage. Induced pluripotent stem (iPS) cells potentially ...
Allogeneic fetal-derived human neural stem cells (hfNSCs) that are under clinical evaluation for several neurodegenerative diseases display a favorable safety profile, but require immunosuppression upon transplantation in patients. Neural progenitors derived from patient-specific induced pluripotent stem cells (iPSCs) may be relevant for autologous ex vivo gene-therapy applications to treat gen...
OBJECTIVE To determine the efficacy of bone marrow cell implantation into the necrotic lesion of the femoral head on clinical symptoms and the progression of osteonecrosis of the femoral head in comparison with core decompression. METHODS We studied nineteen patients and twenty four hips with early stage osteonecrosis of the femoral head. The hips were allocated to either core decompression o...
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