نتایج جستجو برای: hcp5

تعداد نتایج: 58  

Journal: :Annals of the Rheumatic Diseases 2022

Background Genetic contribution to development of chronic damage have been scarcely investigated in systemic lupus erythematosus (SLE). In fact, whereas most studies looked for an association between genetic variants and SLE susceptibility or disease phenotypes, only few focused on the relationship these biomarkers development. Objectives Moving from premises, we firstly analyzed distribution o...

2008
Ying Liu Cynthia Helms Wilson Liao Lisa C. Zaba Shenghui Duan Jennifer Gardner Carol Wise Andrew Miner M. J. Malloy Clive R. Pullinger John P. Kane Scott Saccone Jane Worthington Ian Bruce Pui–Yan Kwok Alan Menter James Krueger Anne Barton Nancy L. Saccone Anne M. Bowcock

A genome-wide association study was performed to identify genetic factors involved in susceptibility to psoriasis (PS) and psoriatic arthritis (PSA), inflammatory diseases of the skin and joints in humans. 223 PS cases (including 91 with PSA) were genotyped with 311,398 single nucleotide polymorphisms (SNPs), and results were compared with those from 519 Northern European controls. Replications...

Journal: :Annals of the Rheumatic Diseases 2021

Background: Psoriatic arthritis (PsA) is a chronic inflammatory joint disease typically associated with psoriasis and classified in the group of spondyloarthritis (1). The pathogenesis based on an interplay different genes interacting several environmental factors including stress, trauma, infections, triggering response related to activation innate acquired immunity tissues organs (2). However...

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