There is growing interest in the use of nontraditional short-term biomarkers of hyperglycemia [fructosamine, glycated albumin, and 1,5-anhydroglucitol (1,5-AG)] to complement fasting glucose and hemoglobin A1c (Hb A1c) for prognosis and management of diabetes (1 ). Within-person variability in Hb A1c and fasting glucose has been previously characterized (2–4), but little is known about the vari...

Hemoglobin (Hb) Rambam, or beta69[E13]Gly-->Asp, has been identified in a German woman also suffering from non-insulin-dependent diabetes mellitus and chronic obstructive pulmonary disease. This is the first observation of this Hb variant in a German family thus far. The detailed evaluation of its structure using electrospray mass spectrometry revealed new minor glycohemoglobin components and s...

AIMS To evaluate the effects of zinc with or without other antioxidants on blood glucose, lipid profile, and serum creatinine in adult diabetics on long-term follow-up. MATERIALS AND METHODS Patients (n = 96) were randomly allocated to three groups: group A (n = 29) was supplemented with oral zinc sulfate (22 mg/day) and multivitamin/mineral (zinc+MVM) preparation; group B (n = 31) was given ...

This study describes the distribution of glycosylated haemoglobin (Hb(A1c)) and glucose concentrations in the combined year 1 (2008-2009), year 2 (2009-2010) and year 3 (2010-2011) of the National Diet and Nutrition Survey (NDNS) rolling programme. The NDNS rolling programme is a nationally representative survey of food consumption, nutrient intakes and nutritional status of people aged 1.5 yea...

BACKGROUND The effect of green tea catechins (GTCs) with or without caffeine on glycemic control is controversial. OBJECTIVE We aimed to identify and quantify the effects of GTCs or GTC-caffeine mixtures on glucose metabolism in adults. DESIGN A comprehensive literature search was conducted to identify relevant trials of GTCs with or without caffeine on markers of glycemic control [fasting ...

OBJECTIVES To review the various hemoglobin (Hb) A1c methods, with a focus on interferences resulting from Hb variants. METHODS HbA1c is a marker used for the diagnosis and management of diabetes. Each available HbA1c method has advantages and challenges, such as its susceptibility to interferences. RESULTS The presence of Hb variants and/or abnormalities in RBC turnover cannot only interfe...

BACKGROUND Although evidence-based guidelines on the management of cardiovascular disease (CVD) and type 2 diabetes have been widely published, implementation of recommended therapies is suboptimal. OBJECTIVE The aim of this study was to evaluate the cost-effectiveness of a comprehensive program of CVD risk reduction delivered by nurse practitioner/community health worker (NP/CHW) teams versu...

duction in neutrophils is induced by G-CSF, and NAP is released into the bloodstream, perhaps through leakage of ALP from damaged or dead neutrophils. Fossa et al. (9 ) reported leukocytosis and increased serum ALP in response to G-CSF treatment and suggested that increased serum ALP activity was related to release of the enzyme from the increased numbers of leukocytes. Neutrophils were reporte...