We show that spatial correlations in a stochastic large scale velocity field in an otherwise smooth intergalactic medium (homogeneous comoving density) superposed on the general Hubble flow, may cause a ‘line-like’ structure in QSO spectra similar to the population of unsaturated Lyα forest lines which usually are attributed to individual clouds with 10 ∼ NHI ∼ 5× 10 13 cm. Therefore there is n...

BACKGROUND Severe unconjugated hyperbilirubinemia carries the risk of neurotoxicity. Phototherapy (PT) and exchange transfusion (ET) are cornerstones in the treatment of unconjugated hyperbilirubinemia. Studies to improve ET efficacy have been hampered by the low application of ET in humans and by the lack of an in vivo model. The absence of an appropriate animal model has also prevented to det...

The observations of Pa\l=r%v\\l=i'\zek& Zahor (1956) and Pa\l=r%v\\l=i'\zek(1957a, b) on the selective destructive effect of cadmium on the testis of the rat and mouse have since been confirmed by Meek (1959), Kar & Das (1960), Gunn, Gould & Anderson (1961), Allanson & Deanesly (1962), Chiquoine (1964), Mason, Brown, Young & Nesbit (1964) and others. During studies on the induction of interstit...

PURPOSE To report the association of Marcus Gunn jaw-winking phenomenon and pseudo inferior oblique overaction. METHODS Case report. RESULTS A 21-year-old woman presented with right eyelid elevation on the chewing movement since infancy. Examination showed that both Marcus Gunn jaw-winking phenomenon and pseudo inferior oblique overaction coexist in this patient. CONCLUSION The associatio...

THE following case of congenital ptosis with Marcus Gunn phenomenon (Gunn, 1883) is interesting because of its unusual association with multiple paradoxical oculo-palpebral movements (Duke-Elder, 1952). Case Report An 18-year-old girl came for cosmetic correction of a congenital ptosis of the right upper lid with alternate divergent strabismus of about 150. The Marcus Gunn phenomenon was also p...

We have previously demonstrated that in mice, the decrease in serum thyroxine (T(4)) level by polychlorinated biphenyls (PCBs) occurs without an increase in the UDP-glucuronosyltransferase (T(4)-UDP-GT) for T(4) glucuronidation, although the PCB-induced decrease in rats is generally thought to occur through induction of T(4)-UDP-GT, UGT1A1, and UGT1A6. In the present study, to further clarify t...

Gunn rats glucuronidate acetaminophen (APAP) at reduced rates and show increased susceptibility to APAP-induced hepatotoxicity. This defect is presumed to involve UDP-glucuronosyltransferase (UGT) 1A6, which is nonfunctional in Gunn rats, but it is currently unclear whether other 1A family members are also involved. In humans, two 1A isoforms are known to be active (1A6 and 1A9) but 1A6 form ha...