Overall, 531 dairy cows were inseminated with the aim to study their reproductive performance following administration of GnRH analogue on different days of estrous cycle with different doses. These cows were divided into six treatment and one control group. Depending upon different treatment groups, Buserelin acetate was injected at a dose of 10.5 µg or 21.0 µg on different days (0, 5 or 12) o...

Pisciculture, to increase the fish production, has a crucial limitation. Fish cultured in land-locked water bodies usually do not breed without the hormonal induction. Technology of fish breeding suffered for a long time due to the lack of suitable commercial product to induce the spawning of economically important fish. Hypophysation technique, where pituitary extract was used to induce the br...

Kisspeptin is the peptide product of KISS-1 gene and endogenous agonist for Kiss1 receptor. It well known that kisspeptin acts centrally, stimulates secretion gonadoliberin (GnRH). Further, also interacts with other neuropeptides such as neurokinin B dynorphin to regulate GnRH pulse generation plays a key role in sexual behavior. This study aimed evaluate effect on male rats' motivation its dep...

BACKGROUND The influence of elevated serum progesterone levels during in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) cycles on pregnancy rates is a matter of continued debate among fertility clinicians. Efforts to resolve this question have been impeded by the various assays used to measure progesterone and the different, arbitrary threshold values for defining 'high' proges...

We and others have previously shown that in the rat and the sheep gonadectomy increases the translational capacity of mRNAs encoding gonadotropin subunits alpha, LH beta and FSH beta. Injection of estradiol or of testosterone or dihydrotestosterone depresses the translational capacity of the mRNAs. After using estradiol to induce progesterone receptors in the pituitary of castrated animals, it ...

OBJECTIVE Microscopic colitis (MC) and irritable bowel syndrome (IBS) are both gastrointestinal disorders with female predominance that affect well-being. Autoantibodies against gonadotropin-releasing hormone (GnRH) have recently been detected in IBS patients. The purpose of this study was to compare gastrointestinal symptoms and well-being in MC female outpatients, with or without coexisting I...

AIM Bovine ovarian cysts are a common cause of economic loss in modern dairy herds. The objective of the present study was to evaluate the reproductive responses to three protocols using hCG, GnRH and cloprostenol when the definite diagnosis of the type of ovarian cyst is/is not possible in dairy cows. MATERIALS AND METHODS A total of 144 lactating dairy cows with ovarian cysts were divided i...

the study was undertaken to compare the efficacy of an estradiol-17β + cidr based protocol with the conventional ovsynch + cidr based protocol for synchrony of wave emergence and ovulation in murrah buffalos. in group i (n=25), on day 0 (beginning of experiment), buffaloes were administered a cidr device (1.38 g p4) and concurrently received 1.5 mg e-17β. on day 9, the cidr was removed and a pr...

Annexin A5 (ANXA5), a member of the structurally related family of annexin proteins, is expressed in pituitary gonadotropes. We previously reported that ANXA5 expression is stimulated by gonadotropin-releasing hormone (GnRH). In the present study, we investigated ANXA5 expression in the anterior pituitary gland of GnRH-deficient mutant hypogonadal (hpg) mice. RT-PCR demonstrated that luteinizin...