The intention of this research was to define the predictive factors for acute esophagitis (AE) in lung cancer patients treated with concurrent chemotherapy and three-dimensional conformal radiotherapy. The data for 72 lung cancer patients treated with concurrent chemoradiotherapy between 2008 and 2010 were prospectively evaluated. Mean lung dose, mean dose of esophagus, volume of esophagus irra...

BACKGROUND Transhiatal esophagectomy for esophageal cancer implies blind manipulation of the intrathoracic esophagus. We report a secure hemostatic method with gauze packing in transhiatal esophagectomy. METHODS The gauze-packing technique is utilized for hemostasis just after removal of the thoracic esophagus during transhiatal esophagectomy. After confirming cancer-free margins, the abdomin...

The glutathione S–transferases (GSTs) are a family of enzymes that play an important role in the prevention of cancer by detoxifying numerous potentially carcinogenic compounds. GSTs conjugate reduced glutathione to a variety of electrophilic and hydrophobic compounds, converting them into more soluble, more easily excretable compounds. Decreased glutathione S–transferase-pi (GSTPI) enzyme acti...

High-grade dysplasia in Barrett esophagus is a marker for future development of cancer and for the existence of synchronous cancer. A significant problem in management is intraobserver and interobserver variation in the diagnosis of high-grade dysplasia in Barrett esophagus, the natural history of which is poorly understood; thus, treatment decisions are problematic. The ability to preserve the...

cell free dna (cfdna) is a genetic biomarker that is present in serum or plasma in high concentration in many types of cancer. identification of circu-lating cancer related dna molecules in serum or plasma is a non-invasive tool for early diagnosis and prognosis in many cancer patients. for this review, study selection and data extraction were performed by the authors. detection of point mutati...

Esophageal cancer is the sixth leading cause of death from cancer worldwide [1]. Due to the esophagus distensible characteristics, patients may not recognize any symptoms until 50% of the luminal diameter is compromised explaining why cancer of the esophagus is generally associated with late presentation and poor prognosis [2]. Esophageal stents are devices used to maintain or restore the lumen...

The esophagus begins at the level of the cricopharyngeus and traverses the length of the neck to pass through the mediastinum. It then pierces the right crus of the diaphragm and after a short abdominal component joins the stomach at the cardia. For descriptive purposes the esophagus is referred to as cervical ( 6 cm), thoracic ( 25 cm), and abdominal ( 4 cm). Surgeons often refer to the esopha...

background: we aimed to evaluate the levels of social support in patients with postoperative esophageal carcinoma and potential effect of social support on generic and ec-specific quality of life. methods: overall, 803 chinese patients with ec were recruited in the high-incidence region- linzhou in henan, china for the observation study. we obtained data on european organization for research an...