Around half of the pregnancies in women with epilepsy are unplanned and choice contraceptive method epileptic is important, since it requires considering their possible pharmacological interactions certain types anti-epileptic drugs. Drugs from this class which induce hepatic enzyme activity may alter metabolism most hormonal methods contraception, affect efficacy. Hormonal contraception regard...

Background and Objective: Epilepsy is a long-lasting central nervous system disorder that is accompany with spontaneous seizures and insufficiency in learning and memory. Now drug treatment is the most common therapy but some patients do not research to suitable control of their seizures with current drugs. Hence, new treatment is needed to help those patients that are unaffected to existing dr...

Epilepsy affects 5 to 10 per 1000 of the general population. It is the third most common neurological disorder after stroke and Alzheimer's disease. Available anti-convulsant drugs effectively control epilepsy in about 50% of the patients. Many epileptic seizures are refractory to current anti-epileptic drugs and safety of the anti-epileptic drugs has always been a concern. Herbal drugs may ser...

Cognitive function of patients on monotherapy specific for their epileptic syndrome has been studied infrequently. We evaluated 7 patients with symptomatic localised epilepsies (SEL) on phenytoin aged 30 +/- 12 (mean +/- standard deviation) years, 8 with idiopathic generalised epilepsies on sodium valproate aged 18 +/- 4 years, 16 with SEL on carbamazepine aged 28 +/- 11 years, and 35 healthy c...

OBJECTIVE To investigate the occurrence of adverse effects of antiepileptic drugs (AED) in chronic epileptic patients in mono or polytherapy. METHOD We evaluated consecutive patients that met the following inclusion criteria: age of 18 years or older, diagnosis of epilepsy for at least one year, stable dose of AED for at least three months. Patients were asked if they had any adverse event re...

Abstract Epilepsy is a common neurological disease caused by synchronous firing of hyperexcitable neurons. Currently, anti-epileptic drugs remain the main choice to control seizure, but 30% patients are resistant drugs, which calls for more research on new promising targets. Neuroinflammation closely associated with development epilepsy. As an important inflammatory factor, high mobility group ...

Therapeutic monitoring of antiepileptic drugs is important in process of optimisation of therapy of epileptic patients. Carbamazepine (CBZ) and Lamotrigine (LMT) are important drugs in therapy of epileptic patients which requires the monitoring of concentration of these drugs in serum. Ourstudy aim was the comparison and interpretation of the results of routine therapeutic monitoring of Carbama...

Paroxysmal kinesiogenic choreoathetosis is rare movement disorder, which is frequently misdiagnosed as an epileptic disorder partly because of a good response to anti-epileptic drugs (Phenytoin sodium). At times these patients are mistaken for a conversion reaction. One such case is described.

INTRODUCTION Epileptic psychoses are categorised as peri-ictal and interictal according to their relationship with the occurrence of seizures. There is a close temporal relationship between peri-ictal psychosis and seizures, and psychosis may present before (preictal), during (ictal) or after seizures (postictal). Epileptic psychoses usually have acute initial and final phases, with a short sym...