An enzymatic method, previously used to determine choline-containing phospholipids in serum, was applied to the estimation of phospholipid concentration in bile. The method combines three enzymatic reactions: a) release of choline by phospholipase D; b) choline oxidation by choline oxidase, a reaction which generates hydrogen peroxide; and c) formation of a red quinone dye by peroxidase. The me...

In the last two decades, the design of longitudinal studies, especially the sample size determination, has received extensive attention (Overall and Doyle 1994; Hedeker et al. 1999; Roy et al. 2007). However, there is little discussion on the relative efficiency of three strategies widely used to analyze randomized clinical trial data: a full longitudinal analysis using all data measured over t...

We discuss the determination of the infrared singularities of massive one-loop 5-point functions with Mellin-Barnes (MB) representations. Massless internal lines may lead to poles in the ε expansion of the Feynman diagram, while unresolved massless final state particles give endpoint singularities of the phase space integrals. MB integrals are an elegant tool for their common treatment. An eval...

Titrimetric estimation of calcium with disodium ethylene diamine tetra-acetate (E.D.T.A., sodium edetate), as performed on serum (Baron and Bell, 1957), cannot be applied directly to most other biological specimens because of their high concentration of phosphate. A high ratio of phosphate to calcium in the material titrated causes a drawnout and inaccurate endpoint. A rapid procedure for calci...

We describe a procedure for the determination of hydrochloric acid concentration in gastric juice by means of a conductometric titration of the 50-fold diluted sample with an aqueous ammonia solution. The conductometric method of endpoint indication leads to a definite location of the equivalence point in the titration of hydrochloric acid. The proposed method is simple and accurate and shows a...

The Padmakar-Ivan (PI) index is a first-generation topological index (TI) based on sums over all edges between numbers of edges closer to one endpoint and numbers of edges closer to the other endpoint. Edges at equal distances from the two endpoints are ignored. An analogous definition is valid for the Wiener index W, with the difference that sums are replaced by products. A few other TIs are d...

Endpoint results are presented for multi-valued cyclic contraction mappings on complete metric spaces (X, d). Our results extend previous results given by Nadler (1969), Daffer-Kaneko (1995), Harandi (2010), Moradi and Kojasteh (2012) and Karapinar (2011).

Methods This French prospective multicenter observational study was conducted in 22 hospitals from March 2013 to September 2014. All patients admitted to the ER with AECOPD as primary diagnosis were considered for inclusion. A previously published clinical prognostic score was computed based on the presence of clinical severity signs at entry, baseline dyspnea grade and age [[1]]. This score al...