The methanol extract of the dried ripe fruits of Alpinia rafflesiana was investigated for its DPPH free radical scavenger constituents. 2',3',4',6'-Tetrahydroxychalcone (7), which has never been isolated from natural sources was found to be most active as a DPPH free radical scavenger with the IC50 value of 55 microM. Other known compounds isolated from this species include 5,6-dehydrokawain (1...

Objective: The objective of the study was to carry out phytochemical profiling essential oils (EOs) and evaluation their anti-microbial activity. Methods: EOs extracted from Cumminum cyminum, Zingiber officinale, Trachyspermum ammi, Alipnia galanga, Cedrus deodara, Elettaria cardamomum using clavenger apparatus. Phytochemical analysis high-performance thin layer chromatography (HPTLC) fingerpri...

The present study was carried out to evaluate the possible synergistic interactions on antibacterial and antioxidant efficacy of essential oils of some selected spices and herbs [bay leaf, black pepper, coriander (seed and leaf), cumin, garlic, ginger, mustard, onion and turmeric] in combination. Antibacterial combination effect was evaluated against six important food-borne bacteria (Bacillus ...

BACKGROUND Tuberculosis is an infectious communicable disease and the causative agent of the disease has over the years developed resistance to streamline chemotherapeutic agents with dire consequences and there is a need for development of new and more potent alternatives. METHODS Constituents of leaves material of Combretum heroroense, Citrus lemon and Apodytes dimidiata were serially extra...

Either the whole plant or plant products having medicinal properties are commonly known as medicinal plants. These medicinal plants are known to possess various phytochemicals, which exhibit more bioactivities such as antibacterial, antifungal, anticancer activity, etc. In this study, Aegle marmelos was collected from Chennai, crude extract of fruit and pulp of the chosen plant was subjected fo...

Orchis latifolia belonging to the family Orchidaceae is extensively used in traditional Indian medicine against a wide spectrum of ailments including dysentery, diarrhoea, chronic fever, wounds, burns, fractures and general weakness. The present study relates to the bioactive extracts from O. latifolia against multidrug resistant (MDR) bacteria and Candida albicans. Methanolic extract of O. lat...

PURPOSE Coleus amboinicus is a medicinal plant traditionally used to treat various diseases such as throat infection, cough and fever, diarrhea, nasal congestion and digestive problems. The plant was explored for endophytic fungi producing antimicrobial agents. METHODS Screening for endophytic fungi producing antimicrobial agents was conducted using agar plug method and antimicrobial activity...

The dichloromethane extract prepared from the underground parts of Eleutherine bulbosa (Miller) Urban (Iridaceae) showed strong activity in the direct bioautography assay with the phytopathogenic fungus Cladosporium sphaerospermum. This assay was used to guide the fractionation of this extract and allowed the isolation of four compounds: the new naphthoquinone eleutherinone[8-methoxy-1-methyl-1...

The antibacterial activity of immune haemolymph Galleria mellonella directed against Escherichia coli D31 was destroyed by Pseudomonas aeruginosa crude proteolytic fraction. This was demonstrated by diffusion well assay and acid gel electrophoresis and subsequent bioautography. On the contrary, lysozyme activity appeared to be insensitive to extracellular proteases of P. aeruginosa when activit...