objective: interaction between genetic and environmental factors is considered as major factors in schizophrenia (scz). it has been shown that dopaminergic and noradrenergic neurotransmission dysfunction play an essential role in the scz pathogenesis. this study aimed to find the impact of functional 19-bp insertion/deletion (ins/del) polymorphism in dopamine beta-hydroxylase (dbh) gene on scz ...

In severe COVID-19 patients the blood level of autoantibodies (IgG) to neurospecific proteins was determined. It defined marked increase in peripheral myelin protein, protein lipid S100 type 2 dopamine receptors and dopamine. At same time, it designate relationship between levels NMDA receptors. High specific IgG SARS-CoV-2 S-Trimer Protein coincided with high

Dopamine concentration abnormalities in the body can cause various disorders and diseases such as Parkinson's, Tourette's syndrome, depression. In this study, graphene oxide (GO) was combined with Fe3O4 to sensitively selectively detect dopamine. The performance evaluated by cyclic voltammetry (CV) differential pulse (DPV) methods. results of testing CV on solution [Fe(CN)6] showed that a modif...

background: release of vascular endothelial growth factor (vegf) by ovaries in response to hcg administration is one of the main mechanisms of ovarian hyper stimulation syndrome. since dopamine/dopamine receptor2 (dp-r2) pathway activity -mediated by vegf/ vascular endothelial growth factor receptor 2 (vegfr-2) signaling-, is associated with angiogenic events, dopamine agonists were used for th...

Introduction: Effects of stress on nervous system activity and development are well defined. In the present study, the effects of maternal stress on dopamine-related behavior in the offspring were studied. Methods: Female pregnant Wistar rats (200 g) were randomly exposed to the noise pollution stress (125 db) for 14 days (5 min/day). The time of exposure was random in order to avoid adaptat...

In the present study, interactions of dopamine receptor agonists and antagonists with water swimming stress (WSS) on naloxone-induced jumping in morphine-dependent mice were examined. Mice were rendered dependent as described in the methods section. The opioid receptor antagonist, naloxone (1 mg/kg), was injected to elicit jumping (as a withdrawal sign). The first group exposed to WSS in the pr...

cofe2o4 magnetic nanoparticles were modified by dopamine (da) and ascorbic acid (aa) as anchors. separation of the da and aa using cofe2o4 magnetic nanoparticles have been studied by investigating the effects of ph, concentration of the da and aa, amount of adsorbents, contact time, ionic strength and temperature. the mechanism of adsorption was also studied. the adsorption of da and aa to the ...

objective(s) the aim of this study was to evaluate the effects of dexamethasone on striatal dopaminergic, glutamatergic and gamma amino butyric acid (gaba) ergic neurotransmission in normal and parkinsonian rats. materials and methods dexamethasone (0.15, 0.30, 0.60 and 0.8 mg/kg) was administered to normal or parkinsonian rats (i.p.) followed by the analysis of the striatal neurotransmitters c...