Abstract A 46-year-old woman with Fitzpatrick skin type V presented sudden-onset accelerated diffuse hair loss. Her other relevant medical history included Graves disease. Trichoscopy showed black dots, broken hairs exclamation mark-like and yellow dots. She was provisionally diagnosed alopecia areata (AA). Laboratory work-up, including complete blood count, liver/renal parameters, antinuclear ...

Abstract Talimogene laherparepvec (T-VEC) is a National Institute for Health and Care Excellence-approved oncolytic viral intralesional immunotherapy licensed unresectable stage III(B)–IV(M1a) melanoma. It genetically modified herpes simplex virus that selectively replicates in tumour cells, leading to local systemic antitumour immune responses, improving overall survival. The randomized phase ...

BACKGROUND Viral warts are a common skin condition, which can range in severity from a minor nuisance that resolve spontaneously to a troublesome, chronic condition. Many different topical treatments are available. OBJECTIVES To evaluate the efficacy of local treatments for cutaneous non-genital warts in healthy, immunocompetent adults and children. SEARCH METHODS We updated our searches of...