Several challenges are associated with current vaccine strategies, including repeated immunizations, poor patient compliance, and limited approved routes for delivery, which may hinder induction of protective immunity. Thus, there is a need for new vaccine adjuvants capable of multi-route administration and prolonged antigen release at the site of administration by providing a depot within tiss...

Using shared resources has created better opportunities in the field of sustainable logistics and procurement. The Multi-Depot Traveling Purchaser Problem under Shared Resources (MDTPPSR) is a new variant (TPP) inbound logistics. In this problem, each depot can purchase its products using other depots, vehicles do not have to return their starting depots. routing problem Multi-Trip, Open Vehicl...

This research present a set-partitioning heuristic to generate populations in a hybrid genetic algorithm (hGA) which is able to solve four different variants of the vehicle routing problem: the multi-depot vehicle routing problem (MDVRP), the heterogeneous fleet and mix decisions (type, size and number of vehicle) (HFMVRP), site dependent vehicle routing problem (SDVRP) and the asymmetric vehic...

N P-hard problem as a total distance minimization problem. Natural extension of the notorious traveling salesperson problem (TSP) with… Delivery vehicles (homogeneous or heterogeneous fleet) have a limited capacity. One or more nodes in the graph (single depot vs. multi-depots) are designated as origins of routes. Each route should emanate from such an origin node. The rest of the nodes are ide...

The Vehicle Routing Problem (VRP) involves the design of a set of minimum cost vehicle routes, originating and terminating at a central depot, for a fleet of vehicles that services a set of customers with known demands. This study contains some information about Logistics and Supply Chain Management. In the second part Distribution Management, which is a more related subject with Vehicle Routin...