The first biosimilar version of a biologic agent used to treat psoriasis (infliximab) entered the Spanish market on February 16 of this year, and more biosimilars can be expected to follow in the coming months and years. Logically, this new situation will have economic repercussions and alter prescribing patterns among dermatologists. In this article, we review regulatory issues related to the ...

In Vietnam, there are no accurate data on tetanus incidence to allow assessment of disease burden or vaccination program efficacy. We analyzed age structure of 786 tetanus cases admitted to a tertiary referral center in Vietnam for three separate years during an 18-year period to examine the impact of tetanus prevention programs, namely the Expanded Program on Immunization (EPI) and the Materna...

Natural orifice transluminal endoscopic surgery (NOTES) is an emerging experimental alternative to conventional surgery that eliminates abdominal incisions and incision-related complications by combining endoscopic and laparoscopic techniques to diagnose and treat abdominal pathology. Natural orifice transluminal endoscopic surgery refers to the method of accessing the abdominal cavity through ...

occurs in regions with ambient temperatures of less than 30C and at least 25mm rainfall monthly for 6 months of the year (Gemmell, 1959). Echinococcus granulosus occurs most commonly along the eastern side of the continent in eastern Victoria, New South Wales and Queensland, in areas associated with the Great Dividing Range, and in the south-western corner of Western Australia (Jenkins and Macp...

Ethanol produced from grain and biodiesel produced from vegetable oils and animal fats are the major renewable liquid fuels being produced in the United States. Cellulosic ethanol and Fischer-Tropsch diesel are also renewable liquid fuels of considerable interest, but additional development is needed before they become significant parts of the renewable liquid fuels market. Thus, the discussion...

Levosimendan is a pyridazinone-dinitrile derivative with positive inotropic and vasodilatory effects that has beneficial effects on myocardial performance. In previous randomized studies levosimendan improved hemodynamics and clinical course, but its effect on prognosis is still unclear. This important issue has limited its use. Although primarily used in the management of acute heart failure s...

OBJECTIVE Describe the current situation of the area Medicine III of CAPES and detect challenges for the next four years of evaluation. METHODS The area's documents and reports of meetings were read from 2004 to 2013 Medicine III Capes as well as reports and evaluation form of each Postgraduate Program (PPG) of the area and the sub-page of the area from the Capes website. The data relating to...